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Anti-PSAP/PAP前列腺酸性磷酸酶抗体
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更新日期：2026/9/8 4:13:14
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产品型号：BY-1879R
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相关标签：PSAP/PAP,前列腺酸性磷酸酶抗体,PSAP/PAP前列腺酸性磷酸酶抗体
详细内容
本公司经销PSAP/PAP，前列腺酸性磷酸酶抗体，克隆类型为polyclonal，宿主来源是Rabbit，PSAP/PAP前列腺酸性磷酸酶抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-1879R
英文名称：Anti-PSAP/PAP
中文名称：前列腺酸性磷酸酶抗体
其他名称：名Prostate Specific Acidic Phosphatase; GLBA; Proactivator polypeptide precursor; Prosaposin; prosaposin （variant Gaucher disease ａnd variant metachromatic leukodystrophy）; SAP1; Saposin A; Saposin B; Saposin B Val; Saposin C; Saposin D; Saposins
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 8.8/58kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, dog, mo, rat
产品介绍：PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, ａnd D, which are similar to each other ａnd are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues ａnd glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein ａnd as an integral membrane protein ａnd has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, ａnd metachromatic leukodystrophy.Function : The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins （coproteins）.Saposin-A ａnd saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase （EC 3.2.1.45） ａnd galactosylceramide by beta-galactosylceramidase （EC 3.2.1.46）. Saposin-C apparently acts by combining with the enzyme ａnd acidic lipid to form an activated complex, rather than by solubilizing the substrate.Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A （EC 3.1.6.8）, GM1 gangliosides by beta-galactosidase （EC 3.2.1.23） ａnd globotriaosylceramide by alpha-galactosidase A （EC 3.2.1.22）. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.Saposin-D is a specific sphingomyelin phosphodiesterase activator （EC 3.1.4.12）.Subunit : Saposin-B is a homodimer.Subcellular Location : Lysosome.Similarity : Contains 2 saposin A-type domains. Contains 4 saposin B-type domains.表达在正常的前列腺、前列腺增生和前列腺肿瘤中。
货号：BY-1879R
英文名称：Anti-PSAP/PAP
中文名称：前列腺酸性磷酸酶抗体
其他名称：名Prostate Specific Acidic Phosphatase; GLBA; Proactivator polypeptide precursor; Prosaposin; prosaposin （variant Gaucher disease ａnd variant metachromatic leukodystrophy）; SAP1; Saposin A; Saposin B; Saposin B Val; Saposin C; Saposin D; Saposins
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 8.8/58kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, dog, mo, rat
产品介绍：PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, ａnd D, which are similar to each other ａnd are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues ａnd glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein ａnd as an integral membrane protein ａnd has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, ａnd metachromatic leukodystrophy.Function : The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins （coproteins）.Saposin-A ａnd saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase （EC 3.2.1.45） ａnd galactosylceramide by beta-galactosylceramidase （EC 3.2.1.46）. Saposin-C apparently acts by combining with the enzyme ａnd acidic lipid to form an activated complex, rather than by solubilizing the substrate.Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A （EC 3.1.6.8）, GM1 gangliosides by beta-galactosidase （EC 3.2.1.23） ａnd globotriaosylceramide by alpha-galactosidase A （EC 3.2.1.22）. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.Saposin-D is a specific sphingomyelin phosphodiesterase activator （EC 3.1.4.12）.Subunit : Saposin-B is a homodimer.Subcellular Location : Lysosome.Similarity : Contains 2 saposin A-type domains. Contains 4 saposin B-type domains.表达在正常的前列腺、前列腺增生和前列腺肿瘤中。
PSAP/PAP,前列腺酸性磷酸酶抗体,PSAP/PAP前列腺酸性磷酸酶抗体
