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Anti-PAX5配对盒基因5抗体
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价格：￥电议
更新日期：2026/9/8 4:13:14
生 产 地：其它
产品型号：BY-1861R
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相关标签：PAX5,配对盒基因5抗体,PAX5配对盒基因5抗体
详细内容
本公司经销PAX5，配对盒基因5抗体，克隆类型为polyclonal，宿主来源是Rabbit，PAX5配对盒基因5抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-1861R
英文名称：Anti-PAX5
中文名称：配对盒基因5抗体
其他名称：名PAX5 expression is not only continuously required for B cell lineage commitment during early B cell development but also for B lineage maintenance. PAX5 is found in most cases of mature ａnd precursor B cell non-Hodgkin lymphomas/leukemias. Pax-5 is not detected in Multiple myeloma ａnd solitary plasmacytoma cell lymphomas do express Pax5 except for those with terminal B cell differentiation. T cell neoplasms do not stain with anti-Pax5; however there is a strong association with CD20 expression.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 43kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The PAX5 gene is a member of the paired box （PAX） family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, ａnd alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein （BSAP） that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS ａnd testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development ａnd spermatogenesis.Subunit : Interacts with DAXX （By similarity）. Binds DNA as a monomer. Binds TLE4.Subcellular Location : Nucleus.Tissue Specificity : Expressed at early B-cell differentiation, in the developing CNS ａnd in adult testis.Similarity : Contains 1 paired domain.同源结构域蛋白（Homeodomain Proteins） PAX-5属于转录抑制因子。在胚胎发育和肿瘤生长中起关键作用。其突变和某些肿瘤的发病有关。Pax-5基因是B细胞生成和B细胞发育的重要转录因子，是B细胞系特异性激活蛋白。在B细胞早期发育阶段，Pax-5能影响CD19、CD20等B细胞特异性基因的表达。它主要分布于前B细胞和成熟B细胞。该蛋白对B细胞和神经元的发育有重要作用。 产品图片Antigen: bs-1861P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 3000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.
货号：BY-1861R
英文名称：Anti-PAX5
中文名称：配对盒基因5抗体
其他名称：名PAX5 expression is not only continuously required for B cell lineage commitment during early B cell development but also for B lineage maintenance. PAX5 is found in most cases of mature ａnd precursor B cell non-Hodgkin lymphomas/leukemias. Pax-5 is not detected in Multiple myeloma ａnd solitary plasmacytoma cell lymphomas do express Pax5 except for those with terminal B cell differentiation. T cell neoplasms do not stain with anti-Pax5; however there is a strong association with CD20 expression.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 43kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The PAX5 gene is a member of the paired box （PAX） family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, ａnd alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein （BSAP） that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS ａnd testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development ａnd spermatogenesis.Subunit : Interacts with DAXX （By similarity）. Binds DNA as a monomer. Binds TLE4.Subcellular Location : Nucleus.Tissue Specificity : Expressed at early B-cell differentiation, in the developing CNS ａnd in adult testis.Similarity : Contains 1 paired domain.同源结构域蛋白（Homeodomain Proteins） PAX-5属于转录抑制因子。在胚胎发育和肿瘤生长中起关键作用。其突变和某些肿瘤的发病有关。Pax-5基因是B细胞生成和B细胞发育的重要转录因子，是B细胞系特异性激活蛋白。在B细胞早期发育阶段，Pax-5能影响CD19、CD20等B细胞特异性基因的表达。它主要分布于前B细胞和成熟B细胞。该蛋白对B细胞和神经元的发育有重要作用。 产品图片Antigen: bs-1861P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bs-0295G-HRP） at 1: 3000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm.
PAX5,配对盒基因5抗体,PAX5配对盒基因5抗体
