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生物素标记的兔抗人IgMbs-0345R-Bio
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详细内容
产品编号 bs-0345R-Bio
英文名称 Rabbit Anti-Human IgM / Biotin antibody
中文名称 生物素标记的兔抗人IgM
别 名 Mouse Anti-Human IgM (Biotin); Immunoglobulin M; 兔抗人-IgM;
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human
产品应用 WB=1:1000-10000, IHC-P=1:100-500, IHC-F=1:100-1000, IF=1:100-1000, ELISA=1:1000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 状 Liquid
浓 度 2.0 mg/ml
免 疫 原 Native Human IgM
亚 型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
保存条件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.
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