当前位置: 阿仪网 > 上海雅吉生物科技有限公司 > 产品展示 > 抗体 > 一抗 > 膜糖蛋白CD200抗体ys-6030R
膜糖蛋白CD200抗体ys-6030R
企业档案
会员类型:旗舰版
已获得阿仪网信誉 等级评定
(0 -40)基础信誉积累,可浏览访问
(41-90)良好信誉积累,可接洽商谈
(91+ )优质信誉积累,可持续信赖
阿仪网旗舰版会员:9年
最后认证时间:
注册号: 【已认证】
法人代表: 【已认证】
参观次数:7948944
手机网站:http://wap.app17.com/c137908/
旗舰版网址:http://www.yajiml.com
详细内容
研究领域 细胞生物 免疫学 细胞表面分子 糖蛋白 淋巴细胞 t-淋巴细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, (predicted: Mouse, Rat, )
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
细胞定位 细胞膜
性 状 Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD200:41-140/278
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Function:
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Subunit:
Interacts with CD200R1.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
SWISS:
P41217
Gene ID:
4345
Database links:
Entrez Gene: 4345 HumanOmim: 155970 HumanSwissProt: P41217 HumanUnigene: 79015 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD200是Ⅰ型膜糖蛋白,为免疫球蛋白超家族的新成员,广泛表达在人类胸腺细胞、B细胞、激活的T细胞、滤泡状树突细胞、神经元及血管内皮上。可表达于B细胞及其增殖性疾病和一部分T细胞。近年来研究发现,CD200与CD200R间的相互作用可以传递抑制性信号减低髓样细胞的活性,改变其迁移。CD200在免疫疾病和抑制排斥反应中作为一种免疫耐受信号,它的一些相关分子在免疫调节中也具有一定的作用。
热门标签:膜糖蛋白CD200抗体,雅吉抗体,一抗













