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转录因子E2F8抗体Ys-4265R
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品牌名称：$brandModel.Title型号：Ys-4265R 原产地：中国大陆 更新时间：2026/11/10 8:31:36
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详细内容
产品编号Ys-4265R
英文名称E2F8
中文名称转录因子E2F8抗体
别 名E2F 8; E2F family member 82; E2F tranｓcription factor 8; E2F-8; E2f8; E2F8_HUMAN; FLJ23311; Tranｓcription factor E2F8.
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, (predicted: Human, Chicken, Pig, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量94kDa
细胞定位细胞核
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human E2F8: 265-360/968
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍This gene encodes a member of a family of tranｓcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012].
Function:
Along with E2F7, inhibitor of E2F-dependent tranｓcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 tranｓcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
Subunit:
Forms heterodimers with E2F7 and, to a lesser extent, homodimers. Dimerization is important for DNA binding.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the E2F/DP family
SWISS:
A0AVK6
热门标签：转录因子E2F8抗体,雅吉抗体
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