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纤维母细胞生长因子5抗体Ys-1257R
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品牌名称：$brandModel.Title型号：Ys-1257R 原产地：中国大陆 更新时间：2026/11/10 8:31:36
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产品编号Ys-1257R
英文名称FGF5
中文名称纤维母细胞生长因子5抗体
别 名FGF 5; FGF-5; FGF5; FGF5_HUMAN; fibroblast growth factor 5; HBGF 5; HBGF-5; heparin binding growth factor 5; Heparin-binding growth factor 5; Smag 82; Smag-82.
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, (predicted: Human, Chicken, Dog, Cow, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量78kDa
细胞定位分泌型蛋白
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FGF5: 151-268/268
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transｆorming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced tranｓcript variants encoding different isoｆorms have been identified. [provided by RefSeq].
Function:
Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
Subunit:
Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in neonatal brain.
Similarity:
Belongs to the heparin-binding growth factors family.
热门标签：纤维母细胞生长因子5抗体,雅吉抗体
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