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人乙肝病毒pre S1蛋白抗体Ys-2327R
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品牌名称：$brandModel.Title型号：Ys-2327R 原产地：中国大陆 更新时间：2026/11/10 8:31:36
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详细内容
产品编号Ys-2327R
英文名称Hepatitis B Virus Surface Antigen
中文名称人乙肝病毒pre S1蛋白抗体
别 名Hepatitis B Virus Surface Antigen; Hepatitis B virus PreS1; Hepatitis B virus pre S1 protein; HBV pre S1 protein; HBSAG_HBVD2; HBSAG_HBVC5; Hepatitis B Virus Major surface antigen; Large envelope protein; Large surface protein; L glycoprotein; Major surface antigen; Large S protein; L-HBsAg; LHB.
抗体来源Rabbit
克隆类型Polyclonal
产品应用WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量31/44kDa
细胞定位细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from HBSAG_HBVD2 pre S1 protein: 31-100/389
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse tranｓcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
Function:
Li-HBsAg interacts with capsid protein and with HDV Large delta antigen. Isoｆorm M associates with host chaperone CANX through its pre-S2 N glycan. This association may be essential for M proper secretion.
Subunit:
Li-HBsAg interacts with capsid protein and with HDV Large delta antigen. Isoｆorm M associates with host chaperone CANX through its pre-S2 N glycan. This association may be essential for M proper secretion.
Subcellular Location:
Virion membrane.
Post-translational modifications:
Isoｆorm M is N-terminaly acetylated at a ratio of 90%, and N-glycosylated at the pre-S2 region.
Myristoylated.
Similarity:
Belongs to the orthohepadnavirus major surface antigen family.
热门标签：人乙肝病毒pre,S1蛋白抗体,雅吉抗体
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