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葡萄糖转运蛋白8抗体Ys-4241R
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品牌名称：$brandModel.Title型号：Ys-4241R 原产地：中国大陆 更新时间：2026/11/10 8:31:36
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详细内容
产品编号Ys-4241R
英文名称GLUT8
中文名称葡萄糖转运蛋白8抗体
别 名Glucose Transporter 8; Glucose transporter type 8; Glucose transporter type X1; GLUT-8; GLUT 8; GLUTX1; SLC2A8; solute carrier family 2 (facilitated glucose transporter) member 8.
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, (predicted: Human, Rat, )
产品应用WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量52kDa
细胞定位细胞浆 细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GLUT8: 401-477/477
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍Glucose transporter 8 is an insulin-regulated facilitative glucose transporter. It binds cytochalasin B in a glucose-inhibitable manner. It appears to be a dual-specific sugar transporter as it can be inhibited by fructose. It is highly expressed in testis, where it is down-regulated by estrogen, but not in testicular carcinoma. Lower amounts are present in most other tissues.
Subunit:
Interacts with AP2B1.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. Insulin induces a change in the intracellular localization and gives rise to insertion in the plasma membrane.
Tissue Specificity:
Highest level of expression in placenta and testis. Highly expressed in adult and pubertal testis, but not prepubertal testis. Lower levels of expression in brain, liver, heart, kidney, fat and skeletal muscle.
Similarity:
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
SWISS:
Q9NY64
热门标签：葡萄糖转运蛋白8抗体,抗体
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