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减数分裂重组蛋白家族REC8抗体Ys-7723R
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详细内容
产品编号Ys⁻⁷723R
英文名称REC8
中文名称减数分裂重组蛋白家族REC8抗体
别 名Cohesin Rec8p; Meiotic recombination protein REC8 homolog; Meiotic recombination protein REC8-like 1; rec8; REC8 homolog (yeast); REC8_HUMAN; REC8L; Rec8L1; Rec8p.
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, (predicted: Dog, Pig, Horse, Rabbit, Guinea Pig, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1ug/Test IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量60kDa
细胞定位细胞核
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human REC8: 22-120/547
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.
Function:
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
Subunit:
Interacts (phosphorylated and unphosphorylated ｆorm) with SMC3. Interacts with SYCP3. Interacts (phosphorylated and unphosphorylated ｆorm) with SMC1B. Does not interact with SMC1A. Interacts with RAD51.
Subcellular Location:
Nucleus. Chromosome.
Tissue Specificity:
Expressed in testis and thymus.
Similarity:
Belongs to the rad21 family.
SWISS:
O95072
Gene ID:
9985
热门标签：减数分裂重组蛋白家族REC8抗体,抗体
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