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甲状腺素5＇脱碘酶3抗体Ys-3902R
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品牌名称：$brandModel.Title型号：Ys-3902R 原产地：中国大陆 更新时间：2026/11/10 8:31:36
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详细内容
产品编号Ys-3902R
英文名称Dio3
中文名称甲状腺素5'脱碘酶3抗体
别 名Type 3 DI; D3; 5DIII; Deiodinase iodothyronine type 3; Deiodinase iodothyronine type III; Dio 3; DIOIII; MGC124117; MGC124118; TXDI3; Type III 5' deiodinase; Type III iodothyronine deiodinase.
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量31kDa
细胞定位细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Dio3: 51-150/278
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive ｍmbedbolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults.
Subunit:
Homodimer. May undergo minor heretodimerization with DIO1 and DIO2.
Subcellular Location:
Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Tissue Specificity:
Expressed in placenta and several fetal tissues.
Similarity:
Belongs to the iodothyronine deiodinase family.
热门标签：甲状腺素5＇脱碘酶3抗体,抗体
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