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粘蛋白4抗体Ys-15412R
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详细内容
产品编号Ys-15412R
英文名称HAPLN4
中文名称透明质酸及粘蛋白4抗体
别 名Brain link protein 2; BRAL 2; BRAL2; HAPLN 4; Hapln4; HPLN4_HUMAN; Hyaluronan and proteoglycan link protein 4; Hyaluronan and proteoglycan link protein 4 precursor; KIAA1926.
抗体来源Rabbit
克隆类型Polyclonal
交叉反应(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量40kDa
细胞定位细胞浆
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HAPLN4: 21-120/402
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍HAPLN4 is a 360 amino acid protein encoded by the human gene HAPLN4. HAPLN4 belongs to the HAPLN family and contains 1 Ig-like C2-type (immunoglobulin-like) domain and two Link domains. HAPLN4 mediates the binding of complexes containing hyaluronic acid. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN4 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN4 may also be involved in the formation of extracellular matrices contributing to perineuronal nets and facilitate the understanding of a functional role of these extracellular matrices. HAPLN4 is widely expressed with highest levels in spleen and placenta.
Function:
Binds to hyaluronic acid and may be involved in formation of the extracellular matrix (By similarity).
Subcellular Location:
Secreted, extracellular space, extracellular matrix (By similarity).
Tissue Specificity:
Expressed predominantly in brain.
Similarity:
Belongs to the HAPLN family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 2 Link domains.
SWISS:
热门标签:粘蛋白4抗体,抗体













