当前位置： 阿仪网 > 上海雅吉生物科技有限公司 > 产品展示 > 抗体 > 一抗 > 肿瘤血管内皮调节蛋白Robo4抗体Ys-5795R
肿瘤血管内皮调节蛋白Robo4抗体Ys-5795R
价格：￥电议
品牌名称：$brandModel.Title型号：Ys-5795R 原产地：中国大陆 更新时间：2026/11/10 8:31:36
支付方式：
- 支付宝 微信 银行转账
产品完善度： 访问次数：556
企业档案
会员类型：旗舰版
已获得阿仪网信誉 等级评定
(0 -40)基础信誉积累，可浏览访问
(41-90)良好信誉积累，可接洽商谈
(91+ )优质信誉积累，可持续信赖
阿仪网旗舰版会员：9年
工商认证 【已认证】
最后认证时间：
注册号： 【已认证】
法人代表： 【已认证】
参观次数：7948944
手机网站：http://wap.app17.com/c137908/
旗舰版网址：http://www.yajiml.com
详细内容
产品编号Ys-5795R
英文名称Robo4
中文名称肿瘤血管内皮调节蛋白Robo4抗体
别 名Magic roundabout; MRB; Robo 4; Roundabout homolog 4; Roundabout homolog 4 magic roundabout; Roundabout homolog 4 Precursor; ROBO4_HUMAN.
抗体来源
克隆类型Polyclonal
交叉反应(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量108kDa
细胞定位细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Robo4: 261-360/1007
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍Robo4 is a vascular specific receptor that is a repulsive cue to migrating endothelial cells during vascular development. Guidance and patterning of axons are orchestrated by cell surface receptors and ligands that provide directional cues. Interactions between the Robo receptor and Slit ligand families of proteins initiate signaling cascades that repel axonal outgrowth. In contrast to known neuronal Robo family members, the arrangement of the extracellular domains of Robo4 diverges significantly from that of all other Robo family members. Robo4 is specifically expressed in the vascular endothelium during murine embryonic development; the only Robo family member expressed in primary endothelial cells. Robo4 also has a role in regulating the migration of endothelial cells during tumor angiogenesis.
Function:
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit protein.
Subunit:
Interacts with SLIT2 and ENAH.
Tissue Specificity:
Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.
Similarity:
Belongs to the immunoglobulin superfamily. ROBO family.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
热门标签：肿瘤血管内皮调节蛋白Robo4抗体,抗体
相关文章
相关产品
-
电议 -
-
-
-
电议
