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细胞骨架4.1蛋白家族DAL1抗体Ys-6003R
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详细内容
产品编号Ys-6003R
英文名称DAL1/EPB41L3
中文名称细胞骨架4.1蛋白家族DAL1抗体
别 名Differentially expressed in adenocarcinoma of the lung protein 1; 4.1B; Band 4.1 like protein 3; DAL 1; DAL1; EPB41L3; Erythrocyte membrane protein band 4.1 like 3; HGNC:3380; KIAA0987; E41L3_HUMAN.
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量120kDa
细胞定位细胞浆 细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human DAL1/EPB41L3: 131-230/1087
亚 型IgG
纯化方法affinity purified by Protein A
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors.
Function:
Critical growth regulator in the pathogenesis of meningiomas.
Subunit:
Interacts with CADM1.
Subcellular Location:
Cytoplasm, cytoskeleton
Tissue Specificity:
Expressed at high levels in brain, with lower levels in kidney, intestine, and testis.
Similarity:
ontains 1 FERM domain.
SWISS:
Q9Y2J2
热门标签:细胞骨架4.1蛋白家族DAL1抗体,抗体













