其他产品及厂家
bi-1935 is an inhibitor of soluble epoxide hydrolase (seh). for diseases related to cardiovascular disease.
更新时间:2025-07-07
bi-3812 is an inhibitor of bcl6. which inhibiting the btb domain of bcl6 (ic50: 3 nm). bi-3812 also has antitumor activity.
更新时间:2025-07-07
bi-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on th2 cells (dp2/crth2). with ic50 values of 4.5 nm and 3.7 nm for pgd2 binding to crth2 in hcrth2 and mcrth2 transfected cells, respectively. bi-671800
更新时间:2025-07-07
deferasirox is an oral iron chelating agent used to treat chronic iron overload.
更新时间:2025-07-07
bifenazate is a positive allosteric modulator of gaba receptor. bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.
更新时间:2025-07-07
biotin-dadoo is a biotinylation reagent,which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-dadoo-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.
更新时间:2025-07-07
biotin hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. biotin hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nucleic acids, and glycoprotiens.
更新时间:2025-07-07
biotin nhs is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
更新时间:2025-07-07
epalrestat, an aldose reductase inhibitor, is well tolerated in long-term therapy. it can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particularly in patients with limited microangiopathy
更新时间:2025-07-07
biotin-peg3-acid is a biotin-labeled, peg-based protac linker that can be used in the synthesis of protacs.biotin-peg3-acid is a heterobiofunctional biotin peg derivative containing a carboxylic acid group. the hydrophilic peg spacer arm imparts water sol
更新时间:2025-07-07
cisatracurium besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration.
更新时间:2025-07-07
biotin-peg3-azide is a peg-based protac linker can be used in the synthesis of protacs.
更新时间:2025-07-07
biotin-peg4-alkyne is a biotin-labeled, peg-based protac linker that can be used in the synthesis of protacs.
更新时间:2025-07-07
dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.
更新时间:2025-07-07
candesartan is an angiotensin ii receptor blocker used widely in the therapy of hypertension and heart failure.
更新时间:2025-07-07
captopril is a potent and specific inhibitor of peptidyl-dipeptidase a. it blocks the conversion of angiotensin i to angiotensin ii, a vasoconstrictor and important regulator of arterial blood pressure.
更新时间:2025-07-07
ramelteon is a melatonin receptor agonist. the mechanism of action of ramelteon is as a melatonin receptor agonist.
更新时间:2025-07-07
bis-peg3-nhs ester is a nonclaevable 3-unit peg linker for antibody-drug-conjugation (adc).
更新时间:2025-07-07
toremifene citrate is a selective estrogen receptor modulator (serm). it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on the mammary and uterine tissue.
更新时间:2025-07-07
mupirocin is a rna synthetase inhibitor antibacterial. it has shown excellent activity against gram-positive staphylococci and streptococci.
更新时间:2025-07-07
nadifloxacin has been used in trials studying the treatment of acne vulgaris.
更新时间:2025-07-07
motixafortide is an antagonist of cxcr4 with ic50 of ～1 nm. it induces the apoptosis of aml blasts by down-regulating erk, bcl-2, mcl-1 and cyclin-d1 via altered mir-15a/16-1 expression.
更新时间:2025-07-07
acemetacin is a carboxymethyl ester of indometacin. it is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. in clinical trials, acemetaci
更新时间:2025-07-07
lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (nsaid) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin bi
更新时间:2025-07-07
bms-986158 is a potent bet inhibitor with ic50s of 6.6 and 5 nm in nci-h211 small cell lung cancer (sclc) cells and mda-mb231 triple negative breast cancer (tnbc) cells, respectively.
更新时间:2025-07-07
bms-986165 inhibits il-12/23 and type i ifn pathways[1][2]. bms-986165 is a highly selective, orally bioavailable allosteric tyk2 inhibitor for the treatment of autoimmune diseases. which selectively binds to tyk2 pseudokinase (jh2) domain (ic50=1.0 nm) a
更新时间:2025-07-07
levocetirizine is a histamine-1 receptor antagonist. the mechanism of action of levocetirizine is as a histamine h1 receptor antagonist.
更新时间:2025-07-07
bmx-in-1 is a selective inhibitor of bone marrow tyrosine kinase on chromosome x (bmx, ic50 = 8 nm) and the related bruton’s tyrosine kinase (btk, ic50 = 10.4 nm), but bmx-in-1 is more than 47-656 fold less potent against blk, jak3, egfr, itk, or tec acti
更新时间:2025-07-07
bnc105 is a tubulin polymerization inhibitor. it has potent antiproliferative and tumor vascular disrupting properties.
更新时间:2025-07-07
fexofenadine is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria.
更新时间:2025-07-07
fexofenadine hydrochloride is a carboxylated metabolic derivative of terfenadine and long-lasting selective histamine h1 receptor antagonist, with antihistaminic activity.
更新时间:2025-07-07
duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for serotonin and noradrenaline (snri). it is an antidepressive agent and anxiolytic and is also used for the treatment of pain in patients with diabetes me
更新时间:2025-07-07
trospium is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. trospium has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.
更新时间:2025-07-07
trilostane is a synthetic derivative of androstane with adrenocortical suppressive properties. trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex.
更新时间:2025-07-07
otilonium bromide, an antimuscarinic, is utilized as a spasmolytic agent.
更新时间:2025-07-07
boc-nh-peg3-ch2cooh is a peg-based protac linker can be used in the synthesis of protac[1].
更新时间:2025-07-07
boc-nh-peg4-ch2cooh is a cleavable adc linker used as a linker for antibody-drug conjugates (adc)[1].
更新时间:2025-07-07
fesoterodine fumarate is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. fesoterodine is rapidly hydrolyzed in vivo into its active metabolite 5-hydroxymethyl
更新时间:2025-07-07
pramipexole is a selective dopamine receptor agonist used in the therapy of parkinson disease. pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not been implicated in cases of clinically appar
更新时间:2025-07-07
bos-172722 is an inhibitor of monopolar spindle 1 (mps1) checkpoint(ic50 of 2 nm).
更新时间:2025-07-07
bph-715 inhibits the liver-stage growth of p. falciparum with an ic50 of 10 μm for p. falciparum exoerythrocytic forms in hepg2 cells.
更新时间:2025-07-07
bp 897 is a potent and selective agonist of dopamine d3 receptor and it is a weak dopamine d2 receptor antagonist, with kis of 0.92 nm and 61 nm for d3 and d2 receptors. which shows low affinities at d1 and d4 receptors (kis, 3 and 0.3 μm, respectively).
更新时间:2025-07-07
bragsin2 is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of afr guanine nucleotide exchange factor brag2 that inhibits arf gtpase activation, with an ic50 of 3 μm. bragsin2 binds at the interface between the pleckstrin hom
更新时间:2025-07-07
brd6989 is an analog of the natural product cortistatin a (dca). which inhibits cdk8 and upregulates il-10. brd6989 inhibits the kinase activity of recombinant cdk8 or cdk19 complexes. brd6989 selectively binds a complex of cdk8 with an ic50 of ~200 nm.
更新时间:2025-07-07
brd7389 is an inducer of insulin expression in pancreatic α-cells and a specific inhibitor of rsk family kinase (ic50s: 1.5 μm, 2.4 μm, and 1.2 μm for rsk1, rsk2, and rsk3).
更新时间:2025-07-07
ondansetron hydrochloride is a competitive serotonin type 3 receptor antagonist. it is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
更新时间:2025-07-07
brilaroxazine is a potent multimodal dopamine/5-ht modulator. brilaroxazine is a partial agonist of dopamine d2, d3, and d4 receptors, 5-ht1a (ki =1.5 nm) and 5-ht2a (ki = 2.5 nm), and has antagonist activity 5-ht2b, and 5-ht7 receptors with kis of 0.19 n
更新时间:2025-07-07
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