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Dionex Acclaim Trinity P1 Series 液相色谱柱
点击次数:212
价格:¥电议
更新日期:2026/9/8 5:02:06
生 产 地:中国大陆
产品型号:美国戴安P/N:071387
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详细内容
产品简介
详细介绍
Acclaim Trinity P1 Series
Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features
- Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
- Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
- Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
- Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents
Acclaim Trinity P1 Applications
- Active pharmaceutical ingredients (API) and counterions (cations or anions)
- Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
- Mixture of acidic and basic drug substances and respective counterions
- Drug substances of acidic, basic, and neutral mixtures
- High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.
技术参数:
| Acclaim Trinity P1 Column – Superior Performance for Pharmaceutical Applications Specifications | |
|---|---|
| Column chemistry | SCX, WAX and RP Mixed-Mode |
| Operating pressure limit (recommended) | 4500 psi (4000 psi) |
| Operating pH range (recommended) | 2.5 – 7.0 (3.0 to 6.2) |
| Operating flow rate range (recommended) | 0.3 – 1.5(0.4 – 0.8) mL/min for 3.0-mm i.d. formats 0.15 – 0.80 (0.2 to 0.4) mL/min for 2.1-mm i.d. formats |
订购信息:
| Analytical Columns | |
|---|---|
| Acclaim Trinity P1, 3?m, 3.0 x 150mm | 075563 |
| Acclaim Trinity P1, 3?m Analytical, (3.0 x 100mm) | 071387 |
| Acclaim Trinity P1, 3?m Analytical, (3.0 x 50mm) | 071388 |
| Acclaim Trinity P1, 3?m, 2.1 x 150mm | 075564 |
| Acclaim Trinity P1, 3?m Analytical, (2.1 x 100mm) | 071389 |
| Acclaim Trinity P1, 3?m, 2.1 x 50mm | 075565 |
| Guard Columns | |
|---|---|
| Acclaim Trinity P1, 3?m Guard Cartridges, (3.0 x 10mm), 2ea (Use Holder V-2) | 071390 |
| Acclaim Trinity P1, 3?m Guard Cartridges, (2.1 x 10mm), 2ea (Use Holder V-2) | 071391 |
| Acclaim SST Guard Cartridge Holder V-2 | 069580 |
| Acclaim Guard Kit (Holder and coupler) V-2 | 069707 |
| Guard to Analytical Column Coupler V-2 | 074188 |



