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Peprotech Recombinant Human IL-17 特价供应

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价格：￥电议

更新日期：2026/8/25 0:21:39

生产地：中国大陆

产品型号：

简单介绍：货号：200-17
名称：Recombinant Human IL-17
品牌：Peprotech
规格：2ug/10ug/

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Peprotech Recombinant Human IL-17 特价供应

Catalog Number:

200-17

Synonyms:

IL-17, CTLA-8

Description:

The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory ａnd hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions ａnd in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human ａnd murine cells. Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.

AA Sequence:

MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

Biological Activity:

Assay #1: The ED₅₀ as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ng/ml.
Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.

Cross Reactivity:

Mouse, Human, Cow

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