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Peprotech Recombinant Human beta-NGF

点击次数：509

价格：￥电议

更新日期：2026/8/25 0:21:39

生产地：中国大陆

产品型号：Peprotech 450-01

简单介绍：产品名称：Recombinant Human beta-NGF
品牌：Peprotech
规格：20ug/100Ug

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详细内容

Peprotech Recombinant Human beta-NGF（450-01）

Catalog Number:

450-01

Synonyms:

NGF-β

Description:

β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 ａnd NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, ａnd plays a crucial role in the development ａnd preservation of the sensory ａnd sympathetic nervous systems. β-NGF also acts as a growth ａnd differentiation factor for B lymphocytes ａnd enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers （240 total amino acid residues）. The three disulfide bonds are required for biological activity.

AA Sequence:

SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

Biological Activity:

determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.

Cross Reactivity:

Chicken, Hamster, Mouse, Rat, Human, Leech

Research Interests: