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进口报价 Peprotech Recombinant Murine IL-1β
点击次数：303
价格：￥电议
更新日期：2026/8/25 0:21:39
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相关标签：Peprotech,Recombinant,Murine,IL-1β,说明书,供应,Peprotech,211-11B
详细内容
进口报价 Peprotech Recombinant Murine IL-1β
Catalog Number:
211-11B
Synonyms:
Catabolin, Lymphocyte-activating factor （LAF）, Endogenous Pyrogen （EP）, Leukocyte Endogenous Mediator （LEM）, Mononuclear Cell Factor （MCF）
Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β binds to the same receptor ａnd has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the ability to stimulate the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.
AA Sequence:
MVPIRQLHYR LRDEKSLV LSDPYELKAL HLNGQNIN VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108units/mg.
Cross Reactivity:
Human, Monkey, Pig, Rat, Mouse + Chicken, Mouse, Mouse + Bacteria, Human + Mouse
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Peprotech,Recombinant,Murine,IL-1β,说明书,供应,Peprotech,211-11B
