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Peprotech Recombinant Human IL-1β 说明书
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更新日期：2026/8/25 0:21:39
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相关标签：批发,Peprotech,Recombinant,Human,IL-1β,,现货供应,Peprotech,200-01B
详细内容
Peprotech Recombinant Human IL-1β 说明书
Catalog Number:
200-01B
Synonyms:
Catabolin, Lymphocyte-activating factor （LAF）, Endogenous Pyrogen （EP）, Leukocyte Endogenous Mediator （LEM）, Mononuclear Cell Factor （MCF）
Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β binds to the same receptor ａnd has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the ability to stimulate the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.
AA Sequence:
APVRSLNCTL RDSKSLVM SGPYELKALH LQGQDMEV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine D10S cells is ≤ 1.0 pg/ml, corresponding to a specific activity of ≥ 1 x 109 units/mg.
Cross Reactivity:
Frog, Monkey, Mouse, Rabbit, Rat, Sheep, Human, Mouse + Chicken, Cow, Human + Rat, Pig
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批发,Peprotech,Recombinant,Human,IL-1β,,现货供应,Peprotech,200-01B
