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Peprotech Recombinant Murine IL-1a 代理商

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价格：￥电议

更新日期：2026/8/25 0:21:39

生产地：中国大陆

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相关标签：Peprotech,211-11A,价格,供应,Peprotech,,Recombinant,Murine,IL-1a

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Peprotech Recombinant Murine IL-1a 代理商

Catalog Number:

211-11A

Synonyms:

Hematopoietin-1, Lymphocyte-activating factor （LAF）, Endogenous Pyrogen （EP）, Leukocyte Endogenous Mediator （LEM）, Mononuclear Cell Factor （MCF）

Description:

IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β binds to the same receptor ａnd has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the ability to stimulate the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1α is an 17.9 kDa protein containing 156 amino acid residues.

AA Sequence:

SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

Biological Activity:

The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is < 0.002 ng/ml, corresponding to a specific activity of > 5 x 10⁸units/mg.

Cross Reactivity:

Mouse, Human, Rat + Chicken

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Peprotech,211-11A,价格,供应,Peprotech,,Recombinant,Murine,IL-1a

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