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低价供应 Peprotech Recombinant Human IGF-1

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价格：￥电议

更新日期：2026/8/25 0:21:39

生产地：中国大陆

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简单介绍：北京杰辉生物技术有限公司：提供外包服务
服务内容：合成肽半原偶联、抗血清制备不低于80ml、抗原亲和柱制备（归客户所有）、纯化部分抗体一般10毫克。多肽半抗原的偶联、亲和层析柱制备（客户提供抗原抗体）

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相关标签：北京现货,Peprotech,100-11,原装进口,Recombinant,Human,IGF-1说明书

详细内容

低价供应 Peprotech Recombinant Human IGF-1

Catalog Number:

100-11

Synonyms:

Insulin-like Growth Factor-I, Somatamedin C, IGF-IA

Description:

The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation ａnd survival of various cell types including muscle, bone, ａnd cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin ａnd relaxin. The IGFs are similar by structure ａnd function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I ａnd IGF-II signal through the tyrosine kinase type I receptor （IGF-IR）, but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal ａnd C-terminal propeptide regions. Recombinant human IGF-I ａnd IGF-II are globular proteins containing 70 ａnd 67 amino acids, respectively, ａnd 3 intra-molecular disulfide bonds.

AA Sequence:

GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

Biological Activity:

The ED₅₀ was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁵units/mg.

Cross Reactivity:

Bacteria, Chicken, Cow, Frog, Horse, Monkey, Mouse, Pig, Rat, Sheep, Tiger Salamander, Hamster, Human, N/A

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北京现货,Peprotech,100-11,原装进口,Recombinant,Human,IGF-1说明书

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