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链脲佐菌素,SIGMA S0130-100MG
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价格：￥电议
更新日期：2026/5/25 18:12:13
生 产 地：中国大陆
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详细内容
链脲佐菌素 SIGMAS0130-100MG
≥75% α-anomer basis, ≥98% （HPLC）, powder
产品编号：S0130
中文名称：链脲佐菌素
英文名称：Streptozocin STZ
CAS号：18883-66-4
分子式：C8H15N3O7
分子量：265.22
纯度：≥98%
保存温度：−20 °C
EC号：242-646-8
MDL号：MFCD00006607
订货信息：
产品规格 价格（RMB）
S0130-100MG 491元
S0130-500MG 1,462元
S0130-1G 2,351元
S0130-5G 10,260元
性能描述
Application
Streptozocin is used to induce Type 1 diabetes for medical research.
General description
Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells.
Biochem/physiol Actions
An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1 Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.
assay
≥75% α-anomer basis
≥98% （HPLC）
form
powder
color
white to off-white
mp
121 °C （dec.）（lit.）
storage temp.
−20°C
