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APP695 (CT)淀粉样肽前体蛋白抗体(C端)

APP695 (CT)淀粉样肽前体蛋白抗体(C端)

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价格:¥电议

更新日期:2026/9/8 4:13:06

生 产 地:其它

产品型号:BY-0347R

简单介绍:本公司经销APP695 (CT),淀粉样肽前体蛋白抗体(C端),克隆类型为polyclonal,宿主来源是Rabbit,APP695 (CT)淀粉样肽前体蛋白抗体(C端)可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

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相关标签:APP695,(CT),淀粉样肽前体蛋白抗体(C端),APP695,(CT)淀粉

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本公司经销APP695 (CT),淀粉样肽前体蛋白抗体(C端),克隆类型为polyclonal,宿主来源是Rabbit,APP695 (CT)淀粉样肽前体蛋白抗体(C端)可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

货号:BY-0347R
英文名称:Anti-APP695 (CT)
中文名称:淀粉样肽前体蛋白抗体(C端)
其他名称:A4 amyloid protein; A4; AAA; ABETA; ABPP; AD 1; AD1; Alzheimer disease 1; Alzheimer disease; Alzheimer's disease amyloid protein; Amyloid beta (A4) precursor protein; Amyloid beta A4 protein; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform c; Amyloid beta A4 protein precursor isoform a; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform c; Amyloid beta protein; Amyloid beta-peptide; Amyloid of aging and alzheimer disease; APP; APP I; APPI; Beta amyloid peptide; Cerebral vascular amyloid peptide; CTFgamma; CVAP; Human mRNA for amyloid A4 precursor of Alzheimer's disease; PN 2; PN II; PN2; PreA4; Protease nexin II.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 76/85kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:Amyloid Precursor Protein (APP) functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. APP is important for neurite growth, neuronal adhesion and axonogenesis. Immature APP (N-glycosylated in the endoplasmic reticulum) moves to the Golgi complex where complete maturation occurs (O-glycosylated and sulfated). After alpha-secretase cleavage, soluble APP is released into the extracellular space and the C-terminal is internalized to endosomes and lysosomes. Some APP accumulates in secretory transport vesicles leaving the late Golgi compartment and returns to the cell surface. APP is expressed in the brain, kidney, heart and spleen of fetal tissues; it is induced during neuronal differentiation. In adult brain, highest expression of APP is found in the frontal lobe of the cortex and in the anterior perisylvian cortex-opercular gyri. Moderate expression in the cerebellar cortex, the posterior perisylvian cortex-opercular gyri and the temporal associated cortex. Defects in APP are a cause of autosomal dominant Alzheimer's disease (AD). APP(Amyloid protein precursor)淀粉样蛋白前体蛋白是一种大的细胞膜蛋白,其N端伸出于细胞外。该蛋白遭到破坏并释放出42个氨基酸的β-淀粉样肽,在老年斑和血管中被发现。这些异常蛋白可能积聚,而导致细胞失调和神经元的损伤。在研究APP与AD的关系中,该抗体十分重要。
APP695,(CT),淀粉样肽前体蛋白抗体(C端),APP695,(CT)淀粉

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