钙结合蛋白Calponin (Basic)抗体

参考价：咨询
型号：
品牌： $brandModel.Title
所属地区：中国大陆
原产地：上海-上海
产品摘要：Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein
thought to be involved in the regulation of smooth muscle contraction.

在线询价索取资料

产品完善度：

更新时间：2026/11/10 14:21:37关注度：1621

关键词标签：钙结合蛋白抗体,Calponin,Clone,26A11

支付方式：

支付宝微信银行转账

产品详情

钙结合蛋白Calponin (Basic)抗体
Clone 26A11
7 mL BOND ready-to-use PA0416 P (HIER)
Antigen Background
Calponin (Basic) is an actin, tropomyosin ａnd calmodulin binding protein
thought to be involved in the regulation of smooth muscle contraction. The
expression of basic calponin is reported to be restricted to smooth muscle
cells ａnd is a marker of the differentiated contractile phenotype of developing
smooth muscle. Vascular smooth muscle cells convert to a synthetic
dedifferentiated phenotype when this protein is lost ａnd this is a key stage in
both atherosclerosis ａnd restenosis of coronary arteries after balloon
angioplasty. It is thought that basic calponin exerts its effect via the cortical
actin cytoskeleton ａnd therefore influences proliferation, the transformed
phenotype ａnd the metastatic potential of tumor cells. Basic calponin mRNA
is expressed in smooth muscle of prostate, bowel ａnd aorta whereas neutral
and acidic calponin mRNAs are expressed in non-smooth muscle tissues
such as heart, placenta, lung, kidney, pancreas, spleen, testis ａnd ovary as
well as in smooth muscle-containing tissues.