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Rabbit IL1 beta Clone cDNA
点击次数：585
价格：￥3990
更新日期：2026/8/25 0:28:22
生 产 地：中国大陆
产品型号：10ug
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详细内容
Specifications:
| Gene: | Rabbit IL1 beta |
| Accession: | NM_001082201 |
| Insert size: | 807 bp |
| Concentration: | 10μg at 0.2μg/μL |
Rabbit IL1 beta cDNA
Plasmid
IL-1 beta protein , IL-1 family members,[ Oryctolagus cuniculus (rabbit)]
Also known as: interleukin-1 beta ; IL1B;IL-1β
Interleukin-1 beta (IL-1β) also known as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene. IL-1β is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome2.
Description
This vector contains the complete ORF for the gene of interest and high-level expression of peptide sequences fused with the 109 aa Trx•Tag thioredoxin protein. It is inserted BamHI to XhoI . The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
Preparation and Storage
Formulation cDNA is provided in 10 mM Tris-Cl, pH 8.0
Shipping Ships at ambient temperature
Stability 1 year from date of receipt when
stored at -20℃ to -80℃
Storage Use a manual defrost freezer and
avoid repeated freeze-thaw cycles.
> GRC-120005 Insert DNA Sequence
1 ATGGCAACAG TACCTGAGCT CACCAGTGAG ATGATGGCTT ACCACAGTGG CAATGAAAAT
61 GACCTGTTCT TTGAGGCCGA TGGTCCCAAT TACATGAAGA GCTGCTTCCA GGACCTGGAC
121 CTCTGCTGTC CAGACGAGGG CATCCAGCTG CGCATCTCCT GCCAACCCTA CAACAAGAGC
181 TTCCGGCAGG TCTTGTCAGT CGTTGTGGCT CTGGAGAAGC TGCGGCAGAA AGCAGTTCCC
241 TGCCCACAGG CCTTCCAGGA TGACGGCCTG AGAACTTTCT TTTCCTTAAT CTTTGAAGAA
301 GAACCCGTCC TCTGCAACAC CTGGGATGAC TACAGTCTTG AGTGTGATGC AGTACGATCA
361 CTGCACTGCA GGCTCCAGGA TGCACAACAG AAATCCTTGG TGTTGTCTGG CACGTATGAG
421 CTGAAAGCTC TCCACCTCAA TGCAGAGAAT CTGAACCAAC AAGTGGTGTT CTCCATGAGT
481 TTTGTGCAAG GAGAAGAAAG TAACGACAAG ATACCTGTGG CCTTGGGCCT CAGGGGGAAG
541 AATCTGTACC TGTCCTGCGT GATGAAAGAC GATAAACCTA CCCTGCAGCT GGAGAGTGTA
601 GACCCCAACC GTTACCCAAA GAAGAAGATG GAAAAACGAT TTGTCTTCAA CAAGATAGAA
661 ATCAAGGACA AGCTGGAATT TGAGTCTGCC CAGTTCCCCA ACTGGTACAT CAGCACCTCT
721 CAGACAGAGT ACATGCCCGT CTTCCTGGGA AACAACAGTG GCGGCCAAGA CCTAATTGAC
781 TTCAGCATGG AATTCGTGTC TTCCTAA
> GRC-120005 Translated Insert Sequence
1 MATVPELTSE MMAYHSGNEN DLFFEADGPN YMKSCFQDLD
41 LCCPDEGIQL RISCQPYNKS FRQVLSVVVA LEKLRQKAVP
81 CPQAFQDDGL RTFFSLIFEE EPVLCNTWDD YSLECDAVRS
121 LHCRLQDA KSLVLSGTYE LKALHLNAEN LNVVFSMS
161 FVQGEESNDK IPVALGLRGK NLYLSCVMKD DKPTLQLESV
201 DPNRYPKKKM EKRFVFNKIE IKDKLEFESA QFPNWYISTS
241 QTEYMPVFLG NNSGGQDLID FSMEFVSS*
