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Rabbit Anti- GPR30

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文件大小：4kb

上传时间：2012/8/20 11:29:55

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上传者：上海瑞齐生物科技有限公司

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Rabbit Anti- GPR30

Catalog Number:Rs-01380R

Quantity size:0.1ml （dilute with pH 7.4 0.01 M PBS or diluent of antibody）

Background: G protein-coupled receptors （GPRs, or GPCRs） contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- ａnd extracellular loops ａnd transduce a variety of hormone, endogenous peptide, ａnd neurotransmitter signals into intracellular effects via G proteins. GRP30 is a member of this family ａnd is an orphan receptor. GPR30 expression has been reported in brain, breast carcinoma, blood, bone marrow, CNS, heart, liver, lung, lymph node, placenta, ａnd spleen. In brain, GPR30 is expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate ａnd putamen. However, unlike other known G protein-coupled receptors, GPR30 localizes to the endoplasmic reticulum, where it specifically binds estrogen ａnd estrogen derivatives.

Specificity : ·anti-GPR30 is a Rabbit monoclonal antibody unconjugated

·specific for GPR30 of human, mouse, rat

·use for western blot, elisa, immunoprecipitation

and immunohistochemistry

·affinity chromatography purification, purity :>95%

·isotype: IgG

·mol wt: 38kDa

Rabbit Anti- GPR30

Application :· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Western blotting 1:100-500

· Optimal working dilutions must be determined by the end user.

Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ºC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Rabbit Anti- GPR30