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2024款维甲酸类乳膏在线式高剪切均质机,过氧化苯甲酰凝胶膏管线式乳化机,皮肤消炎乳膏凝胶研磨分散机,乳膏制备设备
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详细内容
一种采用在线式高剪切乳化机制备痤疮药膏的制备方法:
水相配置: 水相配置:将EDTA,丙二醇及纯净水混合在一起搅拌后与油相一起进行均质制备乳膏
油相配置:称纯净水XXg,搅拌加入丙二醇XXg和泊洛沙姆XXg,搅拌5分钟至混合均匀后加入阿达帕林,过筛后的过氧甲苯酰药后搅拌10分钟后采用IKN均质机均质

高的转速和剪切速率对于获得超细悬浮液是至关重要的,根据一些行业的特殊要求,依肯公司又在ER2000系列的基础上开发了ERS2000系列超高速乳化机,其剪切速度可以达到14000rpm,转子的线速度可以达到44m/s。在该速度范围内,由剪切力所造成的湍流结合门研制的电机可以使粒径范围细化到纳米。剪切力更强,乳液的粒径分布更窄。

影响分散乳化结果的因素有以下几点:
1 分散乳化的形式(批次式和连续式)(连续式比批次好)
2 分散乳化的剪切速率 (越大,效果越好)
3 分散乳化的齿形结构(分为初齿,中齿,细齿,超细齿,越细齿效果越好)
4 物料在分散腔体的停留时间,均质时间(可以看作同等的电机,流量越小,效果越好)
5 循环次数(越多,效果越好,到设备的期限,就不能再好)
IKN模块化设计的主要特点如下:
-直立式腔体结构,物料可以全部进入分散腔;
-无死角;
-良好的表面处理;
-符合CIP/SIP的清洗要求;
-低噪音;
-所有接触物料的材质均为SS316;
-小试、中试到量产,平稳过渡;
-仅需简单的更换功能模块,即可满足分散-悬浮-均质-乳化的不同要求;
-卫生设计,适合食品及制药行业;
-可提供特殊材质满足磨损性及腐蚀性产品处理要求。
高速高剪切均质机选型参考
| 高速高剪切均质机 | 标准流量 L/H | 输出转速 rpm | 标准线速度 m/s | 马达功率 KW | 进口尺寸 | 出口尺寸 |
| ERS 2000/4 | 300~1,000 | 14,000 | 44 | 4 | DN25 | DN15 |
| ERS 2000/5 | 1,000~1,500 | 10,500 | 44 | 11 | DN40 | DN32 |
| ERS 2000/10 | 3,000 | 7,300 | 44 | 30 | DN50 | DN50 |
| ERS 2000/20 | 8,000 | 4,900 | 44 | 45 | DN80 | DN65 |
| ERS 2000/30 | 20,000 | 2,850 | 44 | 75 | DN150 | DN125 |
| ERS 2000/50 | 40,000 | 2,000 | 44 | 160 | DN200 | DN150 |
表中上限处理量是指介质为“水”的测定数据。
Shanghai YI Ken Mechanical Equipment Co., Ltd. is a Si no-German cooperative operation enterprise. Through the introduction of German IKN advanced technology and scientific management mode, Lincoln has formed a complete research and development, manufacturing and marketing system. She keeps pace with the global hybrid emulsification technology, has first-class technical research personnel and production capacity, and provides diversified products and technical services for China and the world. She has developed into a leader in China's fluid high shear hybrid equipment industry
The company mainly research and development, manufacturing, sales of several series in the field of fluid: one emulsification machine, two homogenization machine, three dispersion machine, four cavity grinding, five emulsification pump, six complete sets of equipment and other series. For the mix. , homogenization, suspension, emulsification, wet grinding, powder mixing and other fields to provide high quality solutions, equipment processing material fineness can reach micro and Na Mi level. As a famous supplier in China, Lincoln company advocates an in-depth understanding of the requirements of customers to solve the problems in the process, mixing technology, emulsification homogenization, powder mixing technology and reasonable configuration scheme, to ensure the stable reliability of equipment operation. It has been widely used in petroleum, petrochemical, chemical industry, food, bio-pharmaceutical, nuclear industry, fine chemical industry and other fields, and successfully supporting the national key projects, some products returned to sales abroad, and achieved remarkable economic and social benefits.“
热门标签:维甲酸类乳膏在线式高剪切均质机,过氧化苯甲酰凝胶膏管线式乳化机,皮肤消炎乳膏凝胶研磨分散机,乳膏制备设备。













