人结肠癌细胞HCT-116FH0027
价格：￥1200
品牌名称：富衡型号：FH0027 原产地：中国大陆 更新时间：2026/10/21 7:56:21
产品摘要：HCT-116细胞建系于1979年M. Brattain 团队，48 岁男性结肠癌患者的肿瘤组织（该患者未接受过化疗或放疗），该细胞是结直肠癌研究中代表性的细胞模型之一，因其野生型 p53和MSI-H 特性而在肿瘤学研究中具有独特价值。作为等基因模型的理想亲本，它为探索 p53 功能、DNA 修复机制和肿瘤药物开发提供了重要平台，是癌症研究领域不可替代的工具。
支付方式：
- 支付宝 微信 银行转账
产品完善度： 访问次数：666
企业档案
会员类型：旗舰版
已获得阿仪网信誉 等级评定
61成长值
(0 -40)基础信誉积累，可浏览访问
(41-90)良好信誉积累，可接洽商谈
(91+ )优质信誉积累，可持续信赖
阿仪网旗舰版会员：3年
工商认证 【已认证】
最后认证时间：
注册号： 【已认证】
法人代表： 【已认证】
参观次数：630295
详细内容
| 产品名称 | 人结肠癌细胞；HCT-116 (STR) |
|---|---|
| 品牌 | FuHeng |
| 英文名 | HCT-116 (STR) |
| 货号 | FH0027 |
| 规格 | 1×10⁶cells/T25培养瓶 |
| 培养 | McCOY's5A+10%FBS |
| 别称 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 |
| 形态特征 | 上皮样 |
| 生长特性 | 贴壁生长 |
| 培养基 | HCT-116完全培养基 |
| 培养条件 | 气相：空气，95%；CO2,5%温度：37℃ |
| 传代方法 | 1:3传代，3-4天换液一次 |
| 组织来源 | 结肠腺癌 |
| 细胞简介 | 该细胞系分离自一名50 岁男性患者的结肠腺癌（原发灶，未转移），属于腺癌类型，是研究结直肠癌分子机制及药物开发的经典模型。 |
| 特征特性 | HCT116是1979年M.Brattain等从患结肠癌的男性病人中分离的三株恶性细胞之一。在半固体琼脂糖培养基中形成克隆。HCT116在无胸腺的裸鼠有致瘤性，形成上皮样的肿瘤 |
| 产品名称 | 平滑肌细胞专用培养基 |
|---|---|
| 品牌 | FuHeng |
| 英文名 | smooth muscle cell-specific medium |
| 货号 | FH-N005 |
| 规格 | 500mL/Kit |
| 产品形态 | 液体 |
| 支原体检测 | 阴性 |
| 细胞生长 | 细胞生长良好，形态正常 |
| 储存条件 | 参考说明书 |
| 特别声明 | 富衡细胞库尽最大努力对实验细胞资源相关信息进行及时更新。但限于当时的技术条件，细胞库资料不保证其准确性。 |
上海衡生物科技有限公司
上海富衡生物科技有限公司（以下简称“富衡”）是主要从事生物科技，医药科技领域内的技术开发，技术咨询，技术服务的高新技术企业。是一家专注于细胞相关技术，服务及产品的高科技生命科学和生物技术领域企业。
富衡提供专业的细胞鉴定服务（采用ATCC细胞鉴定准－－STR基因分型技术），并建立完善鉴定，种类齐全的细胞资源库，能为广大科研工作者在发表高质量文章时提供可靠的“细胞鉴定依据”。公司拥有一个蓬勃朝气的年轻团队，不断进取，我们密切注视细胞技术领域的发展，并且于员工的技术和素质培训。团队中博士硕士以上学历人士达80％，有很强的技术支持及研发能力。
专注于细胞培养 PARTNERS 合作伙伴
富衡相关文献
| 论文标题 | DOI | 发表时间 | 期刊 | 影响因子 | 作者列表 |
| NEK8 stabilization via USP51-mediated deubiquitination promotes colorectal cancer progression | 10.1016/j.prp.2025.156346 | 2025-12-29 | PATHOLOGY RESEARCH AND PRACTICE | 3.2 | Yizhang Wang, Min Lin, Meifang Zeng |
| Baicalin triggers ferroptosis to suppress colorectal cancer via SLC25A28-UQCRC2-regulated electron transport chain disruption | 10.1016/j.freeradbiomed.2025.12.039 | 2025-12-26 | FREE RADICAL BIOLOGY AND MEDICINE | 8.2 | Xueting Yao, Hong Lin, Hui Guo, Ying Liu, Hanchen Xu, Weiwei Liu |
| Glycyrrhizic Acid-based Amorphous Networked Nanomaterial Co-encapsulating Curcumin and IR-813: Overcoming the Limitations of Curcumin Through Precise Targeting and pH-responsive Drug Delivery | 10.1007/s12668-025-02329-z | 2025-12-17 | BioNanoScience | 3.2 | Cai Shuaishuai, Hu Jianpeng, Fang Yicheng, Su Pei, Xue Bo, Jin Guofan |
| Single-cell and spatial tranｓcriptomics integration reveals FAM49B promotes tumor-associated macrophages polarization in colorectal cancer via the MK pathway | 10.3389/fimmu.2025.1682637 | 2025-10-31 | Frontiers in Immunology | 5.9 | Tianyu Liu, Quchen Ding, Jin Gou, Chen Lu, Xingming Lu, Jiatong Chen, Yiming E, Lianhong Li, Chongguo Zhang, Xiaojuan Zhu, Chunzhao Yu, Xiagang Luo |
| The integration of single-cell and ｍmbedbolomics reveals the increase of oxidative phosphorylation during the liver ｍmbedstasis of colorectal cancer | 10.1186/s40170-025-00408-z | 2025-10-09 | Cancer & Metabolism | 5.3 | Liu Tianyu, Sun Sizheng, Huang Yicheng, E. Yiming, Li Wenyuan, Xu Fanggui, Liu Zhengxia, Luo Xiagang, Lu Chen, Yu Chunzhao |
| Immune subtyping of lymph node ｍmbedstasis-negative colorectal cancer reveals biomarkers for prognosis and immunotherapy response | 10.1371/journal.pone.0332915 | 2025-09-24 | PLoS One | 2.6 | Wenliang Yuan, Li Liu |
| Increased CDKN2A expression correlates with resistance to platinum-based therapy and decreased infiltration of B lymphocytes in colon adenocarcinoma | 10.1007/s10142-025-01657-3 | 2025-07-03 | FUNCTIONAL & INTEGRATIVE GENOMICS | 3.1 | Gu Ruru, Li Shuai, Yu Bin, Gu Jiaoyang, Guan Bingxin, Wu Honglei |
| Exploring GIPC2 as a key prognostic marker in colorectal cancer linked to enhanced immune response | 10.1016/j.imbio.2025.153090 | 2025-06-17 | IMMUNOBIOLOGY | 2.3 | Jiaoyang Gu, Xing Qi, Bin Yu, Yanan Wang, Liting Zhang, Shuai Li, Yu Xin |
| Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword | 10.1186/s10020-025-01193⁻⁷ | 2025-06-05 | MOLECULAR MEDICINE | 6.4 | Yi Feiyang, Chen Nianzhi, Zhao Maoyuan, Gu Zhili, Yuan Yun, Tang Xuegui, Liu Fang |
| Bardoxolone methyl suppressed colorectal cancer cells in vitro by inhibiting the PI3K signaling pathway | 10.1038/s41598-025-00480-x | 2025-05-05 | Scientific Reports | 3.9 | Zhang Linlin, Huang Qiaoling, Yang Jingqing, Hu Ye |
| Kynurenine promotes the immune escape of colorectal cancer cells via NAT10-mediated ac4C acetylation of PD-L1 | 10.1016/j.clinsp.2025.100658 | 2025-04-16 | Clinics | 2.4 | Zaibiao Wang, Manman Yin, Ruhang Zhou, Ming Li, Jie Peng, Zhengguang Wang |
| RIPK2 promotes colorectal cancer ｍmbedstasis by protecting YAP degradation from ITCH-mediated ubiquitination | 10.1038/s41419-025-07599-9 | 2025-04-04 | Cell Death & Disease | 9.6 | Lu Chen, Liu Hongda, Liu Tianyu, Sun Sizheng, Zheng Yanan, Ling Tao, Luo Xiagang, E Yiming, Xu Yuting, Li Jie, Liu Lei, Miao Lin, Liu Zhengxia, Yu Chunzhao |
| Integrating network pharmacology and experimental validation to uncover the synergistic effects of Huangqi (Radix Astragali Mongolici)-Ezhu (Rhizoma Curcumae Phaeocaulis) with 5-fluorouracil in colorectal cancer models | 10.19852/j.cnki.jtcm.2025.02.004 | 2025-03-10 | Journal of Traditional Chinese Medicine | 2.2 | Xiying TAN, Ruxin GU, Jing TAO, Yu ZHANG, RuiQian SUN, Gang YIN, Shuo ZHANG, Decai TANG |
| Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists | 10.1016/j.bioorg.2025.108307 | 2025-02-23 | BIOORGANIC CHEMISTRY | 4.7 | Hongyan Lin, Shuaijun Cui, Xinye Xu, Qingqing Chen, Jiazi Ge, Dongxuan Ai, Jie Zhu, Yuheng Tao, Liqun Wang, Lingyu Ruan, Wenhao Ge |
| Hypoxia and lipid ｍmbedbolism related genes drive proliferation migration and immune infiltration mechanisms in colorectal cancer subtyping | 10.1038/s41598-025-85809-2 | 2025-01-18 | Scientific Reports | 3.9 | Huang Shansong, Wang Huiying, Cao Jiaqing, Pang Qiang |
| FAM49B drives colorectal cancer progression by stabilizing c-Myc through NEK9 phosphorylation | 10.1002/biof.2158 | 2025-01-08 | BIOFACTORS | 5.0 | Chen Lu, Tianyu Liu, E. Yimin, Lin Miao, Chunzhao Yu, Jianping Zhang, Xiagang Luo |
| Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis | 10.3389/fcell.2024.1480998 | 2025-01-06 | Frontiers in Cell and Developmental Biology | 4.3 | Qiang Pang, Shansong Huang, Xiaodong Li, Jiaqing Cao |
| Augmenting Tumor Lysis and Immune Response through HIFU-armed Oncolytic Virus Delivery System | 10.1016/j.nantod.2024.102571 | 2024-12-02 | Nano Today | 13.2 | Xifeng Qin, Mingyang Liu, Hu Wu, Boshu Ouyang, Xu Zhao, Xiaomin Su, Ruizhe Xu, Huiwen Liu, Jiayi Wu, Yue Liu, Ting Wang, Onder Ergonul, Füsun Can, Jia Li, Lin Lin, Funan Liu, Zhiqing Pang |
| Bismuth oxide nanoparticles inhibit HCT116 colorectal cancer cells by inducing apoptosis, cell cycle arrest and ROS production | 10.1016/j.procbio.2024.11.017 | 2024-11-15 | PROCESS BIOCHEMISTRY | 3.7 | Yongjing Hu, Ying Yin, Jiayan Shi, Ali Bahadur, Kamyar Shameli, Chenxiao Zheng, Xiaodong Zhang, Sin-Yeang Teow |
| Inhibition of Colorectal Cancer Metastasis by Total Flavones of Abelmoschus Manihot via Lncrna AL137782-mediated STAT3/EMT Pathway Regulation | 10.2174/0113816128298998240828060306 | 2024-09-16 | CURRENT PHARMACEUTICAL DESIGN | 2.6 | Qian Li, Hui Zhang, Yongshan He, Hao Zhang, Conghui Han |
| METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and ｍmbedstasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification | 10.1186/s13062-024-00511-z | 2024-08-19 | Biology Direct | 5.7 | Ren Hongtao, Wang Mincong, Ma Xiulong, An Lei, Guo Yuyan, Ma Hongbing |
| Creatine kinase mitochondrial 2 promotes the growth and progression of colorectal cancer via enhancing Warburg effect through lactate dehydrogenase B | 10.7717/peerj.17672 | 2024-06-28 | PeerJ | 2.3 | Shasha Cai, Qingqing Xia, Darong Duan, Junhui Fu, Zhenxing Wu, Zaixing Yang, Changfa Yu |
| Nanobody-Engineered Biohybrid Bacteria Targeting Gastrointestinal Cancers Induce Robust STING-Mediated Anti-Tumor Immunity | 10.1002/advs.202401905 | 2024-06-18 | Advanced Science | 14.3 | Xiaolong Xu, Youbin Ding, Yafang Dong, Haitao Yuan, Peng Xia, Chengming Qu, Jingbo Ma, Huifang Wang, Xiaodong Zhang, Liang Zhao, Zhijie Li, Zhen Liang, Jigang Wang |
| Identification of EGR4 as a prospective target for inhibiting tumor cell proliferation and a novel biomarker in colorectal cancer | 10.1038/s41417-024-00743-1 | 2024-03-08 | CANCER GENE THERAPY | 4.8 | Wang Bangting, Zhang Shijie, Wang Haiyang, Wang Min, Tao Yuwen, Ye Mujie, Fan Zhining, Wang Yan, Liu Li |
| Integrative analysis of single-cell and bulk RNA seq to reveal the prognostic model and tumor microenvironment remodeling mechanisms of cuproptosis-related genes in colorectal cancer | 10.18632/aging.205324 | 2023-12-08 | Aging-US | 5.2 | Bowen Chu, Yaohui Wang, Jiwen Yang, Bohan Dong |
| CircVMP1 promotes glycolysis and disease progression by upregulating HKDC1 in colorectal cancer | 10.1002/tox.24061 | 2023-11-27 | ENVIRONMENTAL TOXICOLOGY | 4.5 | Hong-Yu Chen, Xiang-Nan Li, Lei Yang, Chun-Xiang Ye, Zhi-Lei Chen, Zhen-Jun Wang |
| 6-Shogaol Inhibits the Cell Migration of Colon Cancer by Suppressing the EMT Process Through the IKKβ/NF-κB/Snail Pathway | 10.1177/15347354231172732 | 2023-05-09 | INTEGRATIVE CANCER THERAPIES | 2.9 | Min Chen, Chiin Tong, Qibiao Wu, Zhenghong Zhong, Qida He, Li Zeng, Lu Xiao |
| FOXC2-induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression | 10.1002/iub.2718 | 2023-03-24 | IUBMB LIFE | 4.6 | Junwei Zou, Yong Huang, Yuan Chen, Zhaoying Wu, Hao Xie, Hailang Zhou, Chungen Xing |
| LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathway | 10.32604/or.2022.028225 | 2023-02-09 | ONCOLOGY RESEARCH | 3.1 | YAN ZHUANG, CHUNLAN NING, PENGFEI LIU, YANPENG ZHAO, YUE LI, ZHENCHI MA, LULING SHAN, YINGZHE PIAO, PENG ZHAO, XUN JIN |
| A positive feedback circuit between RN7SK snRNA and m6A readers is essential for tumorigenesis | 10.1016/j.ymthe.2022.12.013 | 2022-12-24 | MOLECULAR THERAPY | 12.91 | Xin Xu, Lifang Ma, Xiao Zhang, Susu Guo, Wanxin Guo, Yikun Wang, Shiyu Qiu, Xiaoting Tian, Yayou Miao, Yongchun Yu, Jiayi Wang |
| IGF2BP3 is an essential N6-methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells | 10.1016/j.mtbio.2022.100503 | 2022-11-24 | Materials Today Bio | 10.761 | Xin Xu, Jiangtao Cui, Hong Wang, Lifang Ma, Xiao Zhang, Wanxin Guo, Xiangfei Xue, Yikun Wang, Shiyu Qiu, Xiaoting Tian, Yayou Miao, Mengyi Wu, Yongchun Yu, Yunhua Xu, Jiayi Wang, Yongxia Qiao |
| The Effect and Related Mechanism of Action of Astragalus Compatible with Curcumin against Colon Cancer Metastasis in Mice | 10.1155/2022/9578307 | 2022-06-10 | Gastroenterology Research and Practice | 1.919 | Jiafei Wu, Decai Tang |
| Licochalcone A inhibits proliferation and promotes apoptosis of colon cancer cell by targeting programmed cell death-ligand 1 via the NF-κB and Ras/Raf/MEK pathways | 10.1016/j.jep.2021.113989 | 2021-03-04 | JOURNAL OF ETHNOPHARMACOLOGY | 4.36 | Xueshuang Liu, Yue Xing, Mingyue Li, Zhihong Zhang, Jingying Wang, MyongHak Ri, Chenghua Jin, Guanghua Xu, Lianxun Piao, Honglan Jin, Hongxiang Zuo, Juan Ma, Xuejun Jin |
| Fraxetin inhibits the growth of colon adenocarcinoma cells via the Janus kinase 2/signal transducer and activator of tranｓcription 3 signalling pathway | 10.1016/j.biocel.2020.105777 | 2020-06-03 | INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | 3.673 | Shuo Ren, Yanwei Xing, Chengbo Wang, Fengqi Jiang, Guangyu Liu, Ziyi Li, Tao Jiang, Yuekun Zhu, Daxun Piao |
| Anticancer activity evaluation of indazolyl-substituted piperidin-4-yl-aminopyrimidines | 10.1007/s00044-020-02531-6 | 2020-03-20 | MEDICINAL CHEMISTRY RESEARCH | 1.783 | Wang Chao, Liu Xiao-Wen, Xiao Ting, Xu Zhi-Qiang, Cao Shuang, Wang Hai-Feng, Yan Qiong-Jiao, Gu Shuang-Xi, Zhu Yuan-Yuan |
| AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and ｍmbedstasis through the NF-κB pathway | 10.1002/mc.23066 | 2019-06-10 | MOLECULAR CARCINOGENESIS | 3.411 | Yanwei Xing, Zhiqiang Zhang, Fengxu Chi, Yang Zhou, Shuo Ren, Zhiwei Zhao, Yuekun Zhu, Daxun Piao |
| Antiｍmbedstasis Effect of Astragalus membranaceus-Curcuma zedoaria via β-Catenin Mediated CXCR4 and EMT Signaling Pathway in HCT116 | 10.1155/2019/9692350 | 2019-05-30 | Evidence-based Complementary and Alternative Medicine | 1.984 | Xiying Tan, Mengting Xu, Fuyan Liu, Ming Xu, Yi Yao, Decai Tang |
热门标签：人结肠癌细胞,HCT-116,HCT-116细胞
