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人肝星形细胞LX-2FH0108
价格：￥电议
品牌名称：富衡型号：FH0108 原产地：中国大陆 更新时间：2026/10/21 7:56:21
产品摘要：LX-2细胞系由科学家Lieming Xu等人于2005年建立，旨在解决原代肝星状细胞培养中存在的获取困难、批次间变异大等问题。LX-2细胞是一种非常重要的人源肝星状细胞系，在肝脏疾病研究，特别是肝纤维化的机制探索和药物研发中扮演着核心角色。
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详细内容
| 产品名称 | 人肝星形细胞；LX-2 (STR) |
|---|---|
| 品牌 | FuHeng |
| 英文名 | LX-2 (STR) |
| 货号 | FH0108 |
| 规格 | 1×10⁶cells/T25培养瓶 |
| 价格 | 1800.0 |
| 培养 | DMEM(高糖)+10%FBS |
| 别称 | Lieming Xu-2 |
| 形态特征 | 星状细胞样 |
| 生长特性 | 贴壁生长 |
| 培养条件 | 气相：空气，95%；CO2,5%温度：37℃ |
| 传代方法 | 1:3传代，2-3天换液一次 |
| 组织来源 | 肝 |
| 细胞简介 | LX-2 细胞系源自一名 59 岁男性肝纤维化患者的肝组织，该患者因慢性肝病（具体病因未公开，可能与肝炎病毒感染或酒精性肝病相关）导致肝纤维化。肝星形细胞（Hepatic Stellate Cells, HSCs）是肝纤维化的核心效应细胞，正常状态下静息时储存维生素 A，活化后转化为肌成纤维细胞样表型，大量分泌细胞外基质（如胶原蛋白 I、III），促进肝纤维化形成。 |
| 培养基 | LX-2完全培养基 |
富衡相关文献
| 论文标题 | DOI | 发表时间 | 期刊 | 影响因子 | 作者列表 |
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| Fibroblast growth factor receptor inhibitors ameliorate ｍmbedbolic dysfunction-associated steatohepatitis by modulating the glycine-glutathione-gut microbiota axis | 10.1016/j.freeradbiomed.2025.08.044 | 2025-08-21 | FREE RADICAL BIOLOGY AND MEDICINE | 8.2 | Hailong Li, Xiaoman Ye, Yayue Hu, Yingjun Wang, Yuting Ding, Ying Yang, Ruiqi Mao, Xi Wu, Huixuan Dong, Kaijun Qiu, Xiaohe Li, Honggang Zhou, Guang Yang, Fubao Zhang, Cheng Yang |
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| Micheliolide Alleviates Hepatic Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via the TrxR1/2-Mediated ROS/MEK/ERK Pathway | 10.3390/ph18030287 | 2025-02-20 | Pharmaceuticals | 4.8 | Yi Liu, Ling Yao, Yuanyuan Liu, Yunheng Yang, Ailing Liang, Honglin He, Yao Lei, Wenfu Cao, Zhiwei Chen |
| Hepatoprotective action mechanism and quantification of soyasaponin Bb in Abri Herba by HPLC and network pharmacology | 10.1016/j.jep.2024.118850 | 2024-09-24 | JOURNAL OF ETHNOPHARMACOLOGY | 4.8 | Xingmei Lin, Chengzhong Zhang, Baokang Huang |
| Hepatoprotective effect of diammonium glycyrrhizinate and neuroprotective effect of piperazine ferulate on AmB-induced liver and kidney injury by suppressing apoptosis in vitro and in vivo | 10.1016/j.toxicon.2024.107795 | 2024-06-05 | TOXICON | 2.6 | Xu He, Xiuhong Peng, Suyu Zhang, Tianfeng Yang, Jian Huo, Yanmin Zhang |
| Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation | 10.1016/j.phymed.2024.155477 | 2024-02-24 | PHYTOMEDICINE | 6.7 | Tian Lan, Ping Li, Si-jia Zhang, Shi-yu Liu, Xi-xi Zeng, Fang Chai, Yu-hua Tong, Zhu-jun Mao, Si-wei Wang |
| Echinacoside Exerts Antihepatic Fibrosis Effects in High-Fat Mice Model by Modulating the ACVR2A-Smad Pathway | 10.1002/mnfr.202300553 | 2024-02-17 | MOLECULAR NUTRITION & FOOD RESEARCH | 4.5 | Jie Liang, Ting Chen, Honglei Xu, Tingfang Wang, Qi Gong, Tingting Li, Xiaoyan Liu, Jing Wang, Yun Wang, Liyan Xiong |
| A three-dimensional (3D) liver–kidney on a chip with a biomimicking circulating system for drug safety evaluation | 10.1039/D3LC00980G | 2024-01-31 | LAB ON A CHIP | 6.1 | Qihong Huang, Tianhao Yang, Yunpeng Song, Wenxuan Sun, Jian Xu, Ya Cheng, Ruixue Yin, Lili Zhu, Mengting Zhang, Lei Ma, Honglin Li, Hongbo Zhang |
| Serum exosome-derived microRNA-193a-5p and miR-381-3p regulate AMPK/TGF-β/Smad2/3 signaling pathway and promote fibrogenesis | 10.14309/ctg.0000000000000662 | 2023-12-15 | Clinical and Translational Gastroenterology | 3.6 | Wang Sihao, Chen Yan, Lei Guanglin, Ma Xuemei, An Linjing, Wang Han, Song Zheng, Lin Li, He Quanwei, Xu Ran, Zhan Xiaoyan, Bai Zhaofang, Yang Yongping |
| Analysis of bioactive components and synergistic action mechanism of ShuGan-QieZhi Capsule for treating non-alcoholic fatty liver disease | 10.1016/j.phymed.2023.155173 | 2023-10-29 | PHYTOMEDICINE | 7.9 | Tong Zhu, Xiaohui Huang, Hongyan Zhu, Jihui Chen, Huijuan Yao, Yufeng Zhang, Haibing Hua, Jian Zhang, Jia Qi |
| Hydronidone ameliorates liver fibrosis by inhibiting activation of hepatic stellate cells via Smad7-mediated degradation of TGFβRI | 10.1111/liv.15715 | 2023-08-28 | LIVER INTERNATIONAL | 6.7 | Xianjun Xu, Yuecheng Guo, Xin Luo, Zhenyang Shen, Zhongshang Sun, Bo Shen, Cui Zhou, Junjun Wang, Jingyi Lu, Qingqing Zhang, Yanping Ye, Ying Luo, Ying Qu, Xiaobo Cai, Hui Dong, Lungen Lu |
| Schizandrin C regulates lipid ｍmbedbolism and inflammation in liver fibrosis by NF-κB and p38/ERK MAPK signaling pathways | 10.3389/fphar.2023.1092151 | 2023-05-23 | Frontiers in Pharmacology | 5.6 | Panpan Chen, Rong Wang, Fangbin Liu, Shengnan Li, Yanqiu Gu, Lei Wang, Yongfang Yuan |
| Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy | 10.1080/13880209.2023.2189908 | 2023-04-03 | PHARMACEUTICAL BIOLOGY | 3.8 | Mingyue Ma, Na Wei, Jieren Yang, Tingting Ding, Anping Song, Lerong Chen, Shuguo Zheng, Huanhuan Jin |
| The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway | 10.1186/s13020-023-00723-x | 2023-02-24 | Chinese Medicine | 4.9 | Wan Guoguo, Chen Zhiwei, Lei Lei, Geng Xiaoyu, Zhang Yi, Yang Congwen, Cao Wenfu, Pan Zheng |
| Salvianolic acid B suppresses hepatic stellate cell activation and liver fibrosis by inhibiting the NF-κB signaling pathway via miR-6499-3p/LncRNA-ROR | 10.1016/j.phymed.2022.154435 | 2022-09-05 | PHYTOMEDICINE | 6.656 | Rong Wang, Shengnan Li, Panpan Chen, Xin Yue, Shaozhan Wang, Yanqiu Gu, Yongfang Yuan |
| Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation | 10.3892/mmr.2021.11944 | 2021-02-26 | Molecular Medicine Reports | 2.952 | He-Ming Huang, Xiao-Ru Zhou, Yan-Jun Liu, Shi-Jie Fan, Li-Ping Liao, Jing Huang, Cui-Cui Shi, Liang Yu, Jin-Jin Pen, Cheng Luo, Yuan-Yuan Zhang, Guang-Ming Li |
热门标签：人肝星形细胞,LX-2,LX-2细胞
