文章关键词：二苯基环辛炔-四聚乙二醇-活性酯，二苯基环辛炔PEG4活性酯，1427004-19-0，DBCO-PEG4-NHS ester，DBCO-PEG4-NHS

一、基本信息

【性质简介】：DBCO, as a powerful copper free click chemical reagent, plays a crucial role in fields such as biomedicine, materials science, ａnd nanotechnology. Its unique reaction characteristics enable it to undergo specific ａnd efficient reactions with primary amine groups under mild neutral or slightly alkaline conditions, thereby constructing stable ａnd functionalized covalent compound bonds. The characteristic of DBCO not only simplifies the reaction steps ａnd improves the reaction efficiency, but also reduces the possible by-products, thereby ensuring the purity ａnd stability of the products. This advantage makes DBCO an ideal choice for connecting biomolecules, synthesizing new materials, ａnd preparing nanoparticles. In addition, the hydrophilic PEG spacer arm carried by DBCO provides convenience for its application in the field of biomedicine. PEG, also known as polyethylene glycol, is a highly hydrophilic polymer that can effectively improve the water solubility of molecules ａnd reduce their non-specific adsorption in living organisms. Therefore, when DBCO binds to biomolecules, the presence of PEG spacer arms can significantly enhance the water solubility of biomolecules, reduce their non-specific interactions in living organisms, ａnd thus improve their stability ａnd biocompatibility in biomedical applications.

【中文名】：二苯基环辛炔-四聚乙二醇-活性酯，二苯基环辛炔PEG4活性酯

【英文名】：DBCO-PEG4-NHS ester，DBCO-PEG4-NHS

【CAS号】：1427004-19-0

【化学式】：C34H39N3O10

【分子量】：649.7

【结构式】：

二、详情介绍

【外观】：固体/粉末

【溶解性】：溶于大部分有机溶剂

【规格】：1g，5g，10g

【纯度】：95%+

【储存条件】：本品应密封避光，储存于阴凉、干燥、通风处，避免反复冻融，储液应该立即使用

【注意事项】：陕西新研博美生物科技有限公司提示，试剂仅用于科学研究或者工业应用等非医疗目的，非药用，非食用！

三、相关试剂

Fmoc-L-Ser(β-D-Glc(Ac)4)-OH

2-Azido-2-deoxy-D-glucose

DOTA PSMA，PSMA 617

28.DOTA-DBCO

NOTA NHS，NOTA NHS ester

p SCN Bn NOTA

p SCN Bn DOTA

p-SCN-Bn-TCMC

DOTAGA-tetra (t-Bu ester)

Maleimido mono amide DOTA

DBCO-PEG4-acid

DBCO-PEG5-acid

DBCO-PEG12-acid

DBCO-PEG24-acid

2-Azido-2-deoxy-D-glucose

DOTA PSMA，PSMA 617

28.DOTA-DBCO

NOTA NHS，NOTA NHS ester

p SCN Bn NOTA

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