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更新时间：2026/10/14 9:23:11关注度：50
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1-(3-Fluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS number 936940-82-8) is a pyrazole derivative substituted with a 3-fluorophenyl and an aldehyde group. Pyrazole derivatives are widely utilized as active pharmaceutical ingredients (APIs) including celecoxib. A novel anti-inflammatory pyrazole derivative, LQFM021, incorporates 1-(3-fluorophenyl)-1H-pyrazole-4-carbaldehyde in its synthesis. The entire synthesis process takes two steps: the functional group conversion of the aldehyde group to a nitrile and the ｆormation of a tetrazole using sodium azide.
1-(3-Fluorophenyl)-1H-pyrazole-4-carbaldehyde is also employed in the synthesis of a pyrazole-based disubstituted urea, serving as an anti-melanoma agent.
| CAS Number | 936940-82-8 |
| Chemical Formula | C10H7FN2O |
| Full Name | 1-(3-Fluorophenyl)-1H-pyrazole-4-carbaldehyde |
| Molecular Weight | 190.17 g/mol |
| Synonyms | N/A |
| Classification / Family | Fluorinated building blocks, Heterocyclic building blocks, Aldehyde building blocks, APIs |
| Purity | 98% |
| Melting Point | N/A |
| Appearance | Brown powder/crystals |
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