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更新时间：2026/10/14 9:23:11关注度：85
关键词标签：4,-,甲氧基,-,3-(三氟甲基),苯胺,4-甲氧基-3-(三氟甲基)苯胺,CAS,393-11-3
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4-Methoxy-3-(trifluoromethyl)aniline (CAS number 393-15⁻⁷) is a derivative of anisidine, with a trifluoromethyl substituent introduced at 3-position. 4-Methoxy-3-(trifluoromethyl)aniline is also referred to as anisole, due to the presence of a methoxybenzene moiety. 4-Methoxy-3-(trifluoromethyl)aniline is commonly utilized as a substrate in organic synthesis for studying amine/aniline-related reactions.
4-Methoxy-3-(trifluoromethyl)aniline is also used for synthesizing substituted bicyclic heterocycles, including quinolines, benzotriazoles and benzimidazoles analogs. These applications are particularly relevant to the development of active pharmaceutical ingredients (APIs), showingstrong antitumor and antiviral activities.
| CAS Number | 393-15⁻⁷ |
| Chemical Formula | C8H8F3NO |
| Full Name | 4-Methoxy-3-(trifluoromethyl)aniline |
| Molecular Weight | 191.15 g/mol |
| Synonyms | 3-(Trifluoromethyl)-p-anisidine, 4-Amino-2-(trifluoromethyl)anisole, 4-Methoxy-3-(trifluoromethyl)benzenamine, 5-Amino-2-methoxybenzotrifluoride |
| Classification / Family | Fluorinated building blocks, Aniline building blocks, Anisidine building blocks, Anisole building blocks, Organic synthesis, Heterocycles |
| Purity | 97% |
| Melting Point | Tm= 58 °C – 60 °C |
| Appearance | Pale pink powder/crystals |
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