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更新时间:2026/10/14 9:23:11关注度:239
关键词标签:4-(Trifluoromethyl)-2-pyridone,4-(三氟甲基)-2,-,吡啶酮,ossila材料
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4-(Trifluoromethyl)-2-pyridone (CAS number 50650-59-4), also known as 2-hydroxy-4-(trifluoromethyl)pyridine, bears the structure of 2-pyridone with an electron deficient trifluoromethyl group at 4-position of the pyridyl ring. 2-Pyridones are well-known organic compounds to form dimers via hydrogen bonding. 4-(Trifluoromethyl)-2-pyridone is a classic example that exists as tautomers, hence also known as 2-hydroxy-4-(trifluoromethyl)pyridine.
The trifluoromethyl group is considered to be one of the most powerful electron withdrawing groups yet with a significant electronegativity between that of fluorine and chlorine. Pyridone is a well known inhibitor for serotonin uptake used to treat major depressive disorder.
| CAS Number | 50650-59-4 |
| Chemical Formula | C6H4F3NO |
| Full Name | 4-(Trifluoromethyl)-2-pyridone |
| Molecular Weight | 163.10 g/mol |
| Synonyms | 2-Hydroxy-4-(trifluoromethyl)pyridine, 4-(Trifluoromethyl)pyridin-2-ol |
| Classification / Family | Pyridone derivatives, Semiconductor synthesis intermediates, Organommbedllic compounds, Photocatalyst |

| Purity | >98% (1H NMR) |
| Melting Point | Tm= 158 °C |
| Appearance | White powder |
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