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更新时间：2026/10/14 9:22:10关注度：1330
关键词标签：245-Trifluorophenylacetic,acid,英国ossila材料B3441,英国ossila代理商
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2,4,5-Trifluorophenylacetic acid (CAS number 209995-38-0) is a phenylacetic acid with three fluorine atoms substituted on the benzene ring. 2,4,5-Trifluorophenylacetic acid is applied as a bifunctional additive for stable and efficient perovskite solar cell. The carboxylic acid group within 2,4,5-trifluorophenylacetic acid interacts with the Pb cluster and passivates the deep-energy-level defects of the perovskites. This leads to an enhancement of power conversion efficiency (PCE) from 22.95% to 24.56% (device structure: FTO/TiO2/2,4,5-Trifluorophenylacetic acid:FAI:PbI/Spiro-OMeTAD:LiTFSI:tBP/Au). Additionally, the hyｄrophobicity of the trifluorobenzene moiety improves the stability of the solar cell, maintaining 93.6% of its initial efficiency when stored in air for 3912 hours.
2,4,5-Trifluorophenylacetic acid is also a precursor for the synthesis of sitagliptin through a four-step reaction with an overall yield of 65%. Sitagliptin is an anti-diabetic medication for the treatment of type-2 diabetes.
| CAS Number | 209995-38-0 |
| Chemical Formula | C8H5F3O2 |
| Full Name | (2,4,5-Trifluorophenyl)acetic acid |
| Molecular Weight | 190.12 g/mol |
| Synonyms | 2,4,5-Trifluorobenzeneacetic acid, 2-(2,4,5-Trifluorophenyl)acetic acid, TFPB |
| Classification / Family | Fluorinated building blocks, Phenylacetic acid building blocks, Perovskite solar cell additives, Solid additive, APIs |
| Purity | 98% |
| Melting Point | Tm = 121 °C – 125 °C |
| Appearance | White powder |
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