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DGCR2蛋白抗体应用说明
点击次数: 56发布时间:2022/2/23 14:27:55
- 上 传 者: 昆山远慕生物科技有限公司
- 上传时间: 2022/2/23 14:27:55
- 文件大小: 13KB
- 文件类型: docx
- 所属分类: 操作维修手册
- 下载次数: 2次
- 查看次数: 56
资料简介: 英文名称 DGCR2 DGCR2蛋白抗体产品介绍 background: Function: Similarity:
中文名称 DGCR2蛋白抗体
别 名 DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12.
说 明 书 0.1ml 0.2ml
研究域 心血管 细胞生物 免疫学 神经生物学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit, Zebrafish, xenopuslaevisorangutan
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500DGCR2蛋白抗体 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGCR2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.
Subcellular Location:
Membrane; Single pass type I membrane protein.
Tissue Specificity:
Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney.
Contains 1 C-type lectin domain.
Contains 1 LDL-receptor class A domain.
Contains 1 VWFC domain.
Database links:
UniProtKB/Swiss-Prot: P98153.1
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