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资料下载
DENN域内含蛋白2D抗体说明书
点击次数: 78发布时间:2021/11/25 15:56:47
- 上 传 者: 上海古朵生物科技有限公司
- 上传时间: 2021/11/25 15:56:47
- 文件大小: 14KB
- 文件类型: docx
- 所属分类: 其它资料
- 下载次数: 3次
- 查看次数: 78
资料简介: 中文名称 DENN域内含蛋白2D抗体 optimal dilutions/concentrations should be determined by the end user. Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. DENN域内含蛋白2D抗体产品介绍 DENND2D is a 471 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as two isoforms as a result of alternative splicing. The DENND2D protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2D maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome. Function : Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Similarity : Contains 1 dDENN domain.
别 名 DEN2D_HUMAN; DENN domain-containing protein 2D; DENN/MADD domain containing 2D; DENND2D.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究域
蛋白分子量 predicted molecular weight: 54 kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human DENND2D
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Contains 1 DENN domain.
Contains 1 uDENN domain.
Database links : UniProtKB/Swiss-Prot: Q9H6A0.2
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