MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) ａnd may be involved in the formation of replication forks ａnd in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, ａnd 7, ａnd has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, ａnd thus regulated by protein kinases CDC2 ａnd CDC7. Double serines at positions 26 ａnd 27 are conserved in rat ａnd mouse. High homology >88% to similar proteins from several other species. Expected broad reactivity to various lysates.
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MCM2 antibody was raised against amino acids 21 - 31 of MCM2 (Human).

ELISAIFIHCWB

HumanMouseRatYeast