上海笃玛生物科技有限公司
第12年
当前位置：阿仪网 > 上海笃玛生物科技有限公司 > 技术文献 > CD59 Antibody (R-79) Catalog Number：OM197298
发布时间：2024/9/5 13:35:35关注度：2657
| Product Name | CD59 Antibody (R-79) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | CD59 is a GPI-anchored glycoprotein that is expressed on leukocytes, vascular endothelial cells, various epithelial cells ａnd placenta. CD59 acts together with CD58 in mediating T cell adhesion ａnd activation, ａnd it may be a second ligand of CD2. CD59 functions as a regulator of the terminal pathway of complement by binding to the C8/C9 components of the assembling membrane attack complex (MAC) on host cell membranes, to s the formation of the lytic pore. CD59 also drives both calcium release ａnd activation of lipid-raft associated signalling molecules such as tyrosine kinases. CD59 gene has two p53-responsive domains that may be implicated in the defense of host cells from damage by the complement system in inflammation, suggesting that p53 could be used to mediate susceptibility of tumor cells to the complement lysis during chemotherapy. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CD59 of mouse ａnd rat origin by WB, IP, IF ａnd ELISA: | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | |
|---|---|
| Tissue Specificity | epie corresponding to amino acids 23-101 representing mature CD59 of rat origin |
| Entrez Gene | 12509 |
|---|
Western blot analysis of CD59 expression in rat brain tissue extract.
| Application Notes | recommended for detection of CD59 of mouse ａnd rat origin by WB, IP, IF ａnd ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
原创作者：上海笃玛生物科技有限公司
相关信息
推荐产品
ELISA试剂盒，动物血清，生化试剂盒，标准品，对照品，试剂，耗材，抗体，培养基，代理进口品牌，实验代测服务
在线咨询5分钟应答
