Anti-MIP2/GRO Beta/CXCL2巨噬细胞炎症蛋白2（ GRＯβ

Anti-MIP2/GRO Beta/CXCL2巨噬细胞炎症蛋白2（ GRＯβ）抗体相关标记 Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5

Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC

英文名称 Anti-MIP2/GRO Beta/CXCL2

Anti-MIP2/GRO Beta/CXCL2巨噬细胞炎症蛋白2（ GRＯβ）抗体中文名称 巨噬细胞炎症蛋白2（ GRＯβ）抗体

别 名 C-X-C motif chemokine 2; Chemokine (C X C motif) ligand 2; Chemokine, CXC motif, ligand 2; CINC 2a; CINC2a; CINC3; CXC chemokine; CXCL 2; CXCL2; MIP2; MIP 2; MIP-2; Cytokine-induced neutrophil chemoattractant 3; GRO 2; GRO b; GRO protein, beta; Gro-beta; GRO2; GRO2 oncogene; GROb; GRObeta; Growth regulated protein beta; GROX; Macrophage inflammatory protein 2 alpha; Macrophage inflammatory protein 2; Melanoma growth stimulatory activity beta; MGSA b; MGSA beta; MGSAbeta; MIP 2; MIP 2a; MIP2 alpha; MIP2; MIP2A; MIP2alpha; SCYB 2; Scyb; SCYB2; Small inducible cytokine subfamily B, member 2.

浓 度 1mg/1ml

说 明 书 0.1ml/100μg 0.2ml/200μg

Anti-MIP2/GRO Beta/CXCL2巨噬细胞炎症蛋白2（ GRＯβ）抗体抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,

产品类型 一抗

研究领域 免疫学 转录调节因子

蛋白分子量 predicted molecular weight: 12kDa

性 状 Lyophilized or Liquid

免 疫 原 KLH conjugated synthetic peptide derived from human MIP2 C-terminus

亚 型 IgG

纯化方法 affinity purified by Protein A

储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

相关产品 免疫组化常用试剂 免疫印迹常用试剂 各种标记二抗

Anti-MIP2/GRO Beta/CXCL2巨噬细胞炎症蛋白2（ GRＯβ）抗体产品介绍GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants ａnd activators, including neutrophil degradation with release of myloperoxidase ａnd other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60% amino acid homology to human GRO alpha ａnd GRO gamma.

Function : Produced by activated monocytes ａnd neutrophils ａnd expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5⁻⁷3) shows a highly enhanced hematopoietic activity.

Subcellular Location : Secreted.

Post-translational modifications : The N-terminal processed form GRO-beta(5⁻⁷3) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.

Similarity : Belongs to the intercrine alpha (chemokine CxC) family.

Database links : UniProtKB/Swiss-Prot: P19875.1