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Peprotech Recombinant Human IL-6(200-06)
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更新日期:2026/8/7 17:39:26
生 产 地:中国大陆
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相关标签:Recombinant,Human,IL-6,Peprotech,200-06,重组人白介素6,细胞因子
详细内容
Peprotech Recombinant Human IL-6(200-06)
Recombinant Human IL-6
产品编号:
200-06
别名:
26 kDa protein,IFN-β2,B cell differentiation factor (BCDF),BSF-2,HPGF,HSF,MGI-2
描述:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
氨基酸序列:
PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107units/mg.
交叉反应:
Monkey, Mouse, Rat
研究领域:
| 血管生成/ 心血管 | 癌症 | ||
| 细胞培养 | 糖尿病/ 体重调节 | ||
| 免疫系统 | 炎症 | ||
| 神经生物学 | 干细胞及分化 | ||
| 创伤修复 | 过敏 | ||
| 移植 |
原产国:
USA
仅用于研究。不适用于诊断或治疗。
Recombinant,Human,IL-6,Peprotech,200-06,重组人白介素6,细胞因子

