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重组小鼠IL-4（214-14）,Recombinant Murine IL-4
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更新日期：2026/8/7 17:39:26
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相关标签：Peprotech,重组小鼠白介素4,Recombinant,Murine,IL-4,代理,Peprotech,214-14
详细内容
重组小鼠IL-4（214-14）,Recombinant Murine IL-4
Recombinant Murine IL-4
Catalog Number:
214-14
Synonyms:
BCGF, BCDF, B cell stimulating factor （BSF-1）
Description:
IL-4 is a pleiotropic cytokine that regulates diverse T ａnd B cell responses including cell proliferation, survival ａnd gene expression. Produced by mast cells, T cells ａnd bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, ａnd IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 ａnd IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production ａnd allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.
AA Sequence:
MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105units/mg.
Cross Reactivity:
Rat, Pig Intestinal Worm, Mouse, Trout, Human, Bacteria, Leech, Parasite, N/A
Research Interests:
 | Apoptosis |  | Cancer |
 | Cell Culture |  | Immune System |
 | Inflammation |  | Proliferation |
 | Stem Cells & Differentiation |  | Allergy |
 | Transplantation | ||
Country of Origin:
USA
Peprotech,重组小鼠白介素4,Recombinant,Murine,IL-4,代理,Peprotech,214-14
