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Peprotech Recombinant Human IL-3（200-03）
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相关标签：Peprotech,Recombinant,Human,IL-3,重组人白介素3,Peprotech,200-03
详细内容
Peprotech Recombinant Human IL-3（200-03）
Recombinant Human IL-3
Catalog Number:
200-03
Synonyms:
MCGF （Mast cell growth factor）, Multi-CSF, HCGF, P-cell stimulation factor
Description:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation ａnd proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil ａnd mast cell lineages. Produced by T cells, mast cells ａnd eosinophils, IL-3 enhances thrombopoieses, phagocytosis, ａnd antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
AA Sequence:
APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQATTLSL AIF
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Cross Reactivity:
Monkey, Human + Mouse, Human, Bacteria, Mouse, Leech
Research Interests:
 | AIDS / HIV |  | Cancer |
 | Cell Culture |  | Immune System |
 | Proliferation |  | Stem Cells & Differentiation |
Country of Origin:
USA
Peprotech,Recombinant,Human,IL-3,重组人白介素3,Peprotech,200-03
