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代理 美国Peprotech Recombinant Murine IL-1β
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更新日期：2026/8/7 17:39:26
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相关标签：北京,,Recombinant,Murine,IL-1β,Peprotech,211-11B,重组小鼠白介素1β细胞因子
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代理 美国Peprotech Recombinant Murine IL-1β
Recombinant Murine IL-1β
Catalog Number:
211-11B
Synonyms:
Catabolin, Lymphocyte-activating factor （LAF）, Endogenous Pyrogen （EP）, Leukocyte Endogenous Mediator （LEM）, Mononuclear Cell Factor （MCF）
Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β binds to the same receptor ａnd has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity ａnd the ability to stimulate the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.
AA Sequence:
MVPIRQLHYR LRDEKSLV LSDPYELKAL HLNGQNIN VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108units/mg.
Cross Reactivity:
Human, Monkey, Pig, Rat, Mouse + Chicken, Mouse, Mouse + Bacteria, Human + Mouse
Research Interests:
 | Angiogenesis/ Cardiovascular |  | Cancer |
 | Diabetes / Weight Regulation |  | Immune System |
 | Inflammation |  | Neurobiology |
 | Proliferation |  | Stem Cells & Differentiation |
 | Wound Healing |  | Allergy |
 | Transplantation | ||
Country of Origin:
USA
北京,,Recombinant,Murine,IL-1β,Peprotech,211-11B,重组小鼠白介素1β细胞因子
