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Recombinant Murine IFN-r,Peprotech315-05

Name: Recombinant Murine IFN-r,Peprotech315-05
Price: 1 CNY

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更新日期：2026/8/7 17:39:26

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简单介绍：Recombinant Murine IFN-r,Peprotech315-05
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Recombinant Murine IFN-r,Peprotech315-05

Recombinant Murine IFN-γ

Catalog Number:

315-05

Synonyms:

Immune Interferon, type II interferon, T cell interferon, MAF

Description:

IFN-γ is an acid-labile interferon produced by CD4 ａnd CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper （CD4+） cells. IFN-γ signaling in antigen-presenting cells ａnd antigen-recognizing B ａnd T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial ａnd anti-tumor responses of macrophages, NK cells, ａnd neutrophils. Human IFN-γ species-specific ａnd is biologically active only in human ａnd primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.

AA Sequence:

MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

Biological Activity:

Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED₅₀ is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁶ units/mg.

Cross Reactivity:

Rabbit, Rat, Mouse, Mouse + Chicken, Human, Cow, N/A, Mouse + Parasite

Research Interests: