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重组人肝细胞生长因子  Recombinant Human HGF

重组人肝细胞生长因子 Recombinant Human HGF

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更新日期:2026/8/25 0:23:10

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简单介绍:重组人肝细胞生长因子 Recombinant Human HGF
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相关标签:重组人肝细胞生长因子,,Recombinant,Human,HGF

详细内容

重组人肝细胞生长因子 Recombinant Human HGF
Catalog Number:
100-39
Synonyms:
Hepatocyte Growth Factor, Scatter Factor (SF), Hepatopoietin (HPTA)
Description:
HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear, polypeptide-precursor glycoprotein containing 697 amino acid residues. Proteolytic processing of this precursor generates the biologically active heterodimeric form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held together by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues. Recombinant Human HGF is an 80.0 kDa polypeptide consisting of 697 amino acid residues.

重组人肝细胞生长因子 Recombinant Human HGF

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重组人肝细胞生长因子,,Recombinant,Human,HGF

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