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PRDM4抗体（N-20）：SC-15253

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价格：￥电议

更新日期：2026/8/24 23:48:41

生产地：美洲

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简单介绍：PRDM4抗体（N-20）：SC-15253
PRDM4 Antibody (N-20) is a goat polyclonal IgG provided at 200 μg/ml
epitope mapping near the N-terminus of PRDM4 of rat origin
recommended for detection of PRDM4 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, ca

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相关标签：PRDM4抗体（N-20）：SC-15253

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PRDM4抗体（N-20）：SC-15253

Product Name	Catalog #	Unit	Price	Qty	Add
PRDM4 Antibody （N-20）	sc-15253	200 µg/ml	$279
PRDM4 （N-20） P	sc-15253 P （peptide）	100 µg/0.5 ml	$61

siRNA Gene Silencers （click product name for more information）

Product Name	Catalog #	Unit	Price
PRDM4 siRNA （h）	sc-106446	10 µM	$258
PRDM4 siRNA （m）	sc-153238	10 µM	$258
PRDM4 （h）-PR	sc-106446-PR	10 µM, 20 µl	$23
PRDM4 （m）-PR	sc-153238-PR	10 µM, 20 µl	$23

shRNA Plasmids （click product name for more information）

Product Name	Catalog #	Unit	Price	Qty	Add
PRDM4 shRNA Plasmid （h）	sc-106446-SH	20 µg	$520
PRDM4 shRNA Plasmid （m）	sc-153238-SH	20 µg	$520

shRNA Lentiviral Particles （click product name for more information）

Product Name	Catalog #	Unit	Price	Qty	Add
PRDM4 shRNA （h） Lentiviral Particles	sc-106446-V	200 µl	$625
PRDM4 shRNA （m） Lentiviral Particles	sc-153238-V	200 µl	$625

Species	Gene Name	Gene ID	Chromosome Location	Isoform （mRNA） Accession #	Protein Accession #	OMIM™ Number

Human	PRDM4	11108	12q23.3	NM_012406	Q9UKN5	605780
Mouse	Prdm4	72843	10 C1		Q80V63	N/A

The positive regulatory （PR） domain defines a family of zinc-finger transcription factors involved in cell differentiation ａnd tumorigenesis （1-5）. One member of the PR domain family is PRDM4, a protein that is differentially controlLED by neurotrophin ａnd serum conditions （2）. PRDM4 is characterized by an internal PR domain ａnd six carboxy-terminal zinc finger motifs （1,3）. PRDM4 interacts with the p75 neurotrophin receptor ａnd is redistributed from the cytoplasm to the nucleus following NGF treatment of transfected cells, suggesting that PRDM4 may provide a downstream transducer for the effects of NGF through the p75 neurotrophin receptor （2）. Under normal growth conditions, PRDM4 is predominantly found in the cytoplasm; however, upon serum-starvation, PRDM4 also translocates into the nucleus （2）. The gene encoding human PRDM4 maps to chromosome 12q23-q24.1, a region involved in harboring tumor suppressor genes, suggesting a role for PRDM4 in events associated with growth arrest （1-3）.

PRDM4抗体（N-20）：SC-15253