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整合素：αL抗体（I21 / 7）：SC-18847

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价格：￥电议

更新日期：2026/8/24 23:48:41

生产地：美洲

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简单介绍：整合素：αL抗体（I21 / 7）：SC-18847
Integrin αL Antibody (I21/7) is a rat monoclonal IgG2a provided at 200 μg/ml
raised against I21/7 hybridoma produced by the fusion of MPC.11.TG.1.7.Oua myeloma cells with splenocytes from a Lewis rat immunized with BW 5147 cell line
recommended for detection of Integrin

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相关标签：整合素：αL抗体（I21,/,7）：SC-18847

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整合素：αL抗体（I21 / 7）：SC-18847

Ordering Information

Product Name	Catalog #	Unit	Price
Integrin αL Antibody （I21/7）	sc-18847	200 µg/ml	$279
Integrin αL Antibody （I21/7） FITC	sc-18847 FITC	100 tests in 2 ml	$292
Integrin αL Antibody （I21/7） PE	sc-18847 PE	100 tests in 2 ml	$303

siRNA Gene Silencers （click product name for more information）

Product Name	Catalog #	Unit	Price	Qty	Add
Integrin αL siRNA （m）	sc-35692	10 µM	$258
Integrin αL （m）-PR	sc-35692-PR	10 µM, 20 µl	$23

shRNA Plasmids （click product name for more information）

Product Name	Catalog #	Unit	Price	Qty	Add
Integrin αL shRNA Plasmid （m）	sc-35692-SH	20 µg	$520

shRNA Lentiviral Particles （click product name for more information）

Product Name	Catalog #	Unit	Price	Qty	Add
Integrin αL shRNA （m） Lentiviral Particles	sc-35692-V	200 µl	$625

Integrins are heterodimers composed of noncovalently associated transmembrane a ａnd b subunits. The 16 a ａnd 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen ａnd Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules （ICAMs）, leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering ａnd ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion ａnd cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration ａnd apoptosis.