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人脐动脉平滑肌细胞
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详细内容
推荐培养基:(SMCM, Cat. No. 1101) 产地:San Diego,US 品牌:ScienCell
储存:液氮
运输:干冰
用途:科研
Vascular smooth muscle cell is the cellular substrate of most significant arterial diseases[1]. The increased growth potential of vascular smooth muscle cells represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate vascular smooth muscle cells expression ICAM-1 and VCAM-1 which may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular diseases [2]. In vitro culture of human VSMC as a model of vascular research has played a critical role and continue to provide information in the pharmacology and therapy of vascular diseases.
HUASMC from ScienCell Research Laboratories are isolated from human umbilical artery. HUASMC are cryopreserved at the end of secondary culture and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HUASMC are characterized by immunofluorescent method with antibodies to alpha-smooth muscle actin and desmin. HUASMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HUASMC are guaranteed to further expand for 15 population doublings in the conditions specified by ScienCell Research Laboratories.
Reference
[1] Schwartz, S. M., Campbell, G. R., Campbell, J. H. (1986) Replication of smooth muscle cells in vascular disease. Circ. Res. 58:427-444.
[2] Braun, M., Pietsch, P., Schror, K., Baumann, G., Felix, S. B. (1999) Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc. Res. 41:395-401.



