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人毛囊外根鞘细胞

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价格：￥电议

更新日期：2026/8/24 23:48:28

生产地：美洲

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简单介绍：人毛囊外根鞘细胞
毛囊外壳环绕毛发纤维周围或在根鞘内部。它与其它上皮成分不同，与表皮连接。毛囊外壳由具有独特的结构特性的几层细胞组成，对毛囊起着重要的作用，例如做为感应器官和皮肤的免疫防卫。免疫组织化学染色表明毛囊外壳包含嵌入式表达前体或干细胞。人类外根鞘细胞表现为重叠的角化细胞，在体外易于广泛培养。

人毛囊外根鞘细胞(HHORSC) 提取于人毛囊外根鞘细胞，原代冻存。每管含有细胞数>5×105 cells/ml，此细胞通过Fibronectin and CD105免疫荧光染色验证，经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。

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推荐培养基:（MSCM, Cat. No. 7501）

产地：San Diego,US
品牌：ScienCell

储存：液氮

运输：干冰

用途：科研

The outer root sheath （ORS） of the hair follicle surrounds the hair fiber ａnd inner root sheath. It is distinct from other epidermal components being continuous with the surface epidermis. The ORS consists of several layers of cells that can be identified with unique ultrastructural properties; plays a part in certain function of the hair follicle which including acts as the sensory organ ａnd immunologic sentinel of the skin. Immunohistochemical staining indicates that the ORS contains nestin-expressing progenitor or stem cells [1]. Human outer root sheath cells represent a repeatedly available source of keratinocytes which can be easily ａnd extensively expanded in culture [2].

HHFORSC from ScienCell Research Laboratories are isolated from human hair follicle ourter root sheath. HHFORSC are cryopreserved at primary culture ａnd delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HHFORSC are characterized by their mesenchymal cell morphology ａnd immunofluorescent method with antibody to fibronectin ａnd CD105. HHFORSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast ａnd fungi. HHFORSC are guaranteed to further expand for 15 population doublings at the condition provided by ScienCell Research Laboratories.

Reference
[1] Li, L., Mignone, J., Yang, M., Matic, M., Penman, S., Enikolopov, G. ａnd Moffman, R. （2003） Nestin expression in hair follicle sheath progenitor cells. PNAS 100:9958-9961.
[2]. Limat, A., Breitkreutz, D., Thiekoetter, G., Klein, C.E., Braathen, L.R., Hunziker, T., Fusenig, N.E. （1995） Formation of a regular neo-epidermis by cultured human outer root sheath cells grafted on nude mice. Transplantation. 59:1032-8.