联系我们

联系人：邓冉

点击查看联系方式

供应分类

产品展示

人膀胱平滑肌细胞

点击次数：273

价格：￥电议

更新日期：2026/8/24 23:48:28

生产地：美洲

产品型号：

简单介绍：人膀胱平滑肌细胞
膀胱是由平滑肌细胞组成的中空器官。膀胱平滑肌的舒张和收缩使得膀胱分别储存和排出尿液。膀胱平滑肌细胞表型的调控和可诱导一氧化氮合酶的表达与多种病理状况有关，包括膀胱功能障碍。研究表明，组织缺氧抑制人类膀胱平滑肌细胞的增殖，膀胱平滑肌细胞的分化依赖于膀胱上皮细胞释放的因子。膀胱平滑肌细胞外基质的分泌表型可通过细胞所经历的机械变形频率而改变。平滑肌是许多疾病中的共同路径，因此，了解在疾病发生及持续过程中平滑肌怎样变化，这是治疗方法取得进展的重要一步。

人膀胱平滑肌细胞 (HBdSMC)提取于人膀胱组织，原代冻存。每管含有细胞数>5×105 cells/ml，此细胞通

商家名片

邓*

联系我时，请说明是阿仪网看到的，谢谢!

电话: 02*******563
手机: 18******401
微信:
交换名片后展示联系方式 → →

详细内容

推荐培养基:（SMCM, Cat. No. 1101）

产地：San Diego,US
品牌：ScienCell

储存：液氮

运输：干冰

用途：科研

The urinary bladder is a hollow organ made up of smooth muscle cells. The relaxation ａnd contraction of urinary bladder smooth muscle allows the bladder to store ａnd void urine, respectively. Phenotypic modulation of bladder smooth muscle cells ａnd the expression of inducible nitric oxide synthase are associated with various pathological conditions, including bladder dysfunction [1]. Studies have shown that hypoxia inhibits human bladder smooth muscle cell proliferation [2] ａnd bladder smooth muscle cell differentiation is dependent on the factor（s） released from urothelial cells [3]. The secretory phenotype of bladder smooth muscle cell ECM can be altered by the frequency of mechanical deformation experienced by the cells. Since smooth muscle is the final common pathway for many diseases, to understand how smooth muscle changes during the genesis ａnd maintenance of a disease is an important step toward the development of therapeutic approaches.

HBdSMC from ScienCell Research Laboratories are isolated from human bladder tissue. HBdSMC are cryopreserved at secondary culture after purification ａnd delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HBdSMC are characterized by immunofluorescent method with antibodies to -smooth muscle actin ａnd desmin. HBdSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast ａnd fungi. HBdSMC are guaranteed to further expand for 15 population doublings in the condition provided by ScienCell Research Laboratories.

Reference
[1] Johansson, R. ａnd Persson, K. （2004） Phenotypic modulation of cultured bladder smooth muscle cells ａnd the expression of inducible nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 286（4）:R642-8.
[2] Galvin, D. J., Watson, R. W., O＇Neill, A., Coffey, R. N., Taylor, C., Gillespie, J. I., Fitzpatrick, J. M. （2004） Hypoxia inhibits human bladder smooth muscle cell proliferation: a potential mechanism of bladder dysfunction. Neurourol Urodyn 23（4）:342-8.
[3] Liu, W., Li, Y., Hayward, S., Cunha, G. ａnd Baskin, L. （2000） Diffusable growth factors induce bladder smooth muscle differentiation. In Vitro Cell Dev Biol Anim. 36（7）:476-84.

人膀胱平滑肌细胞